Gyn Infections Flashcards
1st line ttt of AGW in pregnancy and outaide pregnancy
Outside: podophyllotoxin
In pregnancy: Cryotherapy
What are low and high risk types of HPV
Low: 6,11 -> condyloma acuiminata
High: 16,18 -> 70% of cancer Cervix
Is HPV an indication for CS
No , doesn’t decrease vertical transmission
What vaccine to give for HPV
Gardasil 9
When to vaccinate against HPV
Boys and girls 12-13 y (grade 8-9)
The commonest STI in the UK
HPV
Method of transmission of genital HPV
may be by skin to skin contact, not just penetrative sexual intercourse
HPV types of genital warts
6,11
High risk types HPV that may cause cx cancer
16, 18 (cause 70% of cases of cancer cx)
31,33, 35, 39
45,51
All high risk types HPV cause 90% of cancer cx
How do HPV cause cancer
E6 and E7 gene inactivate tumour suppressor genes, which may lead to
carcinogenic transformation
Prevelence of chlamydia before 25 y
5-10%
Symptoms of chlamydia
- asymptomatic 70% f - 50% m
- vaginal discharge
- intermens. And postcoital bleeding
- deep dysparunia
- dysuria
Complications of chlamydia
- 16% if untreated -> clinical PID
- 1-20% if untreated-> infertile
- perihepatitis (sexually acquired reactive arthritis)
- Reiter syn
- rectal infection( proctitis - mucopurulent anal discharge)
Reiter syndrome triad
Urethritis
Arthritis
Conjunctivitis
•The incidence of chlamydial infection in pregnant women is
6%
Antibiotic treatment reduced chlamydia positivity in pregnant women by 90%.
Neonatal infection by chlamydia
30% of exposed infant
- ophthalmia
-lung infection - Nasopharinx and genital infection
Neonatal infection by chlamydia ttt
Treated with erythromycin
Signs of Systemic inflammatory response syndrome
Temp >38 or <36
HR >90
RR >20
PaCO2 <32
TLC >12 or <4
