Throat/Mouth Flashcards

1
Q

What is the health status of the oral cavity linked to?

A

Cardiovascular disease
Diabetes
Systemic Illnesses

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2
Q

What should you assume head and neck infections or swelling to?

A

Odontogenic in origin

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3
Q

What is a dental carie?

A

Infection that is bacterial in origin and causes demineralization and destruction of the hard tissues of the teeth

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4
Q

What can cause a dental carie?

A

A dry mouth

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5
Q

What mouth disease remains one of the most common diseases throughout the world?

A

Dental carie

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6
Q

What are risk factors for dental infection?

A
Low socioeconomic status/ poor access to care
Poor oral hygiene
Poor nutrition
Inadequate fluoride 
Decreased saliva flow
Use of anticholinergic medications
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7
Q

How do we prevent dental problems?

A
Flossing
Brushing with fluoride toothpaste 
Biannual cleaning
Avoid smoking
Good control of systemic diseases
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8
Q

What pathogen causes dental infections?

A

Streptococcus mutants

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9
Q

What dental diseases are common in pregnant women?

A

Pregnancy gingivitis caused by hormonal changes which promote pathogen growth

Pyogenic granuloma

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10
Q

What disease is a systemic risk factor for periodontal disease?

A

Diabetes

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11
Q

What are the two main clinical presentations of periodontal disease?

A

Sensitivity to hot or cold stimuli

Pain on biting

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12
Q

If a child < 4 comes in with a stiff neck, sore throat, and dysphagia, what should they be worked up for?

A

Retropharyngeal abscess secondary to molar infection

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13
Q

What labs might you obtain if a patient has periodontal disease and when is the only time you would obtain these?

A

If the patient looks extremely ill —>

CBC with differential
Culture and sensitivity to test for aerobic and anaerobic pathogens

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14
Q

What might you use a CT scan for with periodontal disease?

A

TO determine the extent and density of swelling, as well as, the location of an abscess within soft tissue or bone

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15
Q

What differential diagnoses might you consider with periodontal disease?

A

Sinusitis

Jaw pain is an angina equivalent in postmenopausal women or long-term diabetic patients

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16
Q

What is the first line treatment for dental infection?

A

Penicillin VK

Loading dose of 1000mg followed by 500mg QID for 7-10 days

IN kids its 40-60 mg/kg/day divided four times a day

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17
Q

What is the second line treatment for dental infection and when should you use it?

A

If there is a longstanding infection or previously treated infection that does not respond to first line; or PCN allergy

Oral Clindamycin 300mg TID for 7-10 days

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18
Q

If a patient has a severe dental infection, what should the treatment be?

A

Loading dose of CLINDAMYCIN 600mg or 900mg IV, then 300mg every 6 hours

COnsider double coverage with metronidazole

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19
Q

What must be obtained before a patient with a dental infection can be released from the hospital?

A

Dental consult and follow up dental care appointment scheduled

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20
Q

What anti inflammatory agents should be used in dental infection?

A

Aspirin or NSAIDS

Careful with opioids

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21
Q

What is the criteria for admission to the hospital for patient with dental infection?

A
Swelling involving deep spaces (pre-fascial planes) of neck
Unstable vital signs
Fever
Chills
Confusion or delirium 
Evidence of invasvie infection
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22
Q

If a patient has an I&D for their dental infection, what is the treatment?

A

Warm salt water rinses several times a day to encourage drainage

Chlorhexidine gluconate twice a day

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23
Q

When can you discharge a patient from the hospital after they are admitted for a dental infection?

A

If airway is not compromised

If abscess and sepsis are eliminated

If the patient is able to take PO and ambulate

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24
Q

What should be avoided in young children in order to prevent dental caries?

A

Sleeping with a bottle

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25
What are potential complications of dental infections?
Ludwig angina Vincent's angina Retropharyngeal abscess/infection Mediastinal infection
26
What is ludwig angina?
sublingual cellulitis with or without tracking abscess inferiorly
27
What is Vincent's angina?
trench mouth acute necrotizing ulcerative gingivitis
28
What are the two clinical pearls of dental infections?
Do not ignore toothache pain | Treat patients with facial swelling aggressively, as infections can quickly spread
29
What is tonsillitis?
inflammation of palatine tonsil glands
30
What is pharyngitis?
Inflammation of any structure of the pharynx, including adenoids and lingual tonsils
31
When is tonsillitis and pharyngitis usually seen?
winter and early spring
32
What virus typically causes tonsillitis or pharyngitis?
Rhinovirus
33
What bacteria typically causes tonsillitis or pharyngitis?
GABHS: Strep pyogenes or GAS
34
What are the clinical manifestations of viral tonsillitis/pharyngitis?
Chronic sore throat and symptoms of common cold ``` Coryza Cough Malaise Fatigue Hoarseness ```
35
What symptoms are associated with viral tonsillitis/pharyngitis caused by mono?
Viral symptoms Posterior LAD Kissing tonsils Hepatosplenomegaly
36
What are the clinical manifestations of Bacterial tonsillits/pharyngitis?
Lack of cough, coryza, or other URI symptoms Sudden onset of sore throat Anterior LAD Fever Petechiae of soft palate
37
What can bacterial tonsillits/pharyngitis lead to in children?
Scarlett fever (GABHS Pharyngitis)
38
What are the clinical manifestations of Scarlett fever?
strawberry tongue | Sandpaper rash on trunk and armpits
39
What are the general symptoms of Tonsillitis/pharyngitis?
``` Dysphagia Odynophagia Sore throat Fever LAD Exudate Headache N/V Abdominal pain ```
40
What do we use to diagnose GABHS pharyngitis/tonsillitis?
Centor Criteria
41
What is the centor criteria?
Fever Anterior LAD Tonsillar exudate Absence of cough 1 symptom = likelihood low for strep 2-3 symptoms = confirm via rapid strep test 4 symptoms = treat for strep pharyngitis
42
What do we treat Adult bacterial pharyngitis with?
Pen VK 500MG twice a day for 10 days
43
What do we treat child bacterial pharyngitis with?
Amoxicillin 50mg/kg PO every day for 10 days or 24 mg/kg PO twice a day for 10 days
44
What is the secondline treatment for bacterial pharyngitis if the patient has a penicillin allergy?
Cephalexin or Macrolide
45
What is the treatment for viral pharyngitis?
``` Gargle with warm water Antipyretics Analgesis for bad cases of mono Rest Decadron single dose if tonsils are really enlarged IVF if dehydrated ```
46
What are the complications of strep pharyngitis/tonsillitis?
Peritonsilar abscess Rheumatic fever Glomerulonephritis
47
What is the most common complication seen with strep pharyngitis/tonsillitis?
Peritonsilar abscess
48
What is a peritonsilar abscess?
Collection of pus located between the capsule of palatine tonsil and pharyngeal muscles
49
What are the causative steps of peritonsilar abscess?
Tonsillitis/pharyngitis --> cellulitis --> abscess
50
What is considered the most common deep space infection of the head and neck?
peritonsilar abscess
51
What is a peritonsilar abscess caused by?
GABHS Others: S. aureus Neisseria Corynebacterium
52
What are the clinical manifestations of peritonsilar abscess?
Severe sore throat that is unilateral | Muffled/"hot potato voice"
53
What are other symptoms of peritonsilar abscess?
``` Fever Ipsilateral ear pain Fatigue Irritability Decreased PO intake Trismus Neck pain with movement Unilateral, swollen, and fluctuant tonsil with contralateral deviation of uvula Pooling of saliva/drooling Neck swelling Rancid or fetor breath Erythema or exudate of the tonsil ```
54
What are differential diagnoses of peritonsilar abscess?
``` Retropharyngeal abscess Ludwig angina Dental infection Peritonsilar cellulitis Infectious mononucleosis ```
55
What typically occurs after patient has had viral pharyngitis?
peritonsilar cellulitis
56
What is the diagnostic tool used to diagnose a peritonsilar abscess?
CT neck with IV contrast
57
If you get an xray of the neck and see a positive thumb sign, what is diseased?
epiglottis
58
When would you get imaging for a peritonsilar abscess?
If you are uncertain about your diagnosis
59
How is a peritonsilar abscess treated?
Drainage Empiric antibiotics --> Augmentin 875 mg twice a day for 14 days or Unasyn IV or clindamycin IV Antipyretics Analgesia
60
What is rheumatic fever?
Delayed, non-suppurative sequelae of GABHS pharyngitis involving lesions of joints, heart, subcutaneous tissue, and CNS
61
What is the concern with rheumatic fever?
lifelong complications and damage to cardiac valves
62
What are the clinical manifestations of rheumatic fever?
``` Carditis/Valvulitis Migratory arthritis Erythema marginatum Sydenhaum chorea Subcutaneous nodules ```
63
What symptoms are assocaited with carditis/valvulitis in rheumatic fever?
Occurs mostly in kids and lasts long-term 30-60% of patients get this on first occurence Effects pericardium, epicardium, myocardium, and valves MITRAL VALVE IS MOST AFFECTED Pericardial friction rub New murmur CHF symptoms
64
What are the symptoms associated with migratory arthritis?
``` Lasts 4 weeks Seen in older teens/adults 75% will get on first occurence Asymmetric pattern Large joints effected Edema Swollen joints ```
65
What are the symptoms associated with erythema marginatum?
lasts weeks to months Seen in kids and rarely adults 10% will get on first attack Non-pruritic, serpinginous erythematous eruption on the trunk Effects trunk more than proximal extremities Non-pruritic rash
66
What are the symptoms associated with sydenhaum chorea?
``` Lasts 2-3 years Seen in children and rarely in adults Females are most likely to get this 25% will get on first occurence Neurological and pyschological components Abrupt rhythmic, purpseless movement Emotionally labile ```
67
What are the symptoms associated with Subcutaneou nodules?
``` Rare and assocaited with carditis Persists for 1-2 weeks Rare to get Painless nodules over tendon sheaths Occurs on elbows, wrist, ankles, and achilles ```
68
How do we diagnose Rheumatic fever?
Jones criteria
69
What is the Jones criteria?
Evidence of recent strep infection + 2 major Or 1 major and 2 minor Or 3 minor if recurrent
70
What are the major symptoms associated with Jones' criteria?
``` Migratory arthritis Carditis/valvulitis Sydenhaum chorea Erythema marginatum Subcutaneous nodules ```
71
What are the minor symptoms associated with Jones' criteria?
Arthralgia Fever Elevated ESR or CRP Prolonged PR interval
72
How are adults with rheumatic fever treated?
Pen VK 500mg twice a day for 10 days | Bed rest until fever is gone and labs/EKG normalize
73
How are children with rheumatic fever treated?
Pen VK 250 mg twice a day for 10 days | Bed rest until fever is gone and labs/EKG normalize
74
What is the secondary prophylaxis treatment for rheumatic fever?
PCN Benzathine G 1.2 million units IM every 4 weeks for 5 years without carditis or 10 years with carditis
75
What is post-streptococcal glomerulonephritis?
Kidney injury caused by a strep infection from impetigo or sore throat that can cause nephritis
76
What is nephritis syndrome?
inflammation of glomerulus
77
Where is post-strep glomerulonephritis most common?
in developing countries
78
What are the clinical manifestations of post-strep glomerulonephritis?
``` Edema Hematuria Hypertension Oliguria Proteinuria ```
79
What are some nonspecific symptoms associated with post-strep glomerulonephritis?
General malaise Weakness Anorexia N/V
80
How do we diagnose post-strep glomerulonephritis?
Urine dip and microscopy to test for hematuria/proteinuria and RBC casts Streptozyme test Rapid strep/strep culture Renal function for increased BUN/Creatinine which would signify AKI
81
What antigens does the streptozyme test test for?
``` Anti-Dnase B Antinicotinamide-adenine dinucleotiase (Anti-NAD) Antistreptokinase (ASKase) Antihyaluronidase (Ahase) Antistreptolysin (ASO) ```
82
How would we treat post-strep glomerulonephritis?
``` Treat the underlying condition Symptomatic/supportive care: Restrict water and salt intake +/- diuretics for edema HTN control with diuretics, CCB, and ACE's Limit activity +/- dialysis if needed ```
83
What is laryngitis?
inflammation of vocal fold mucosa and larynx
84
What is the funciton of the larynx?
Voice | Prevent aspiration of food
85
What is acute laryngitis caused by?
``` VIRUS bacteria GERD Environmental Vocal trauma ```
86
How long is acute laryngitis?
Resolves in 7-10 days
87
How long is chronic laryngitis?
> 3 weeks
88
What are the clinical manifestations of laryngitis?
Hoarseness (dysphonia) Preceding or concurrent URI symptoms like cough and rhinitis Odynophonia Odynophagia
89
What is the treatment for laryngitis?
VOICE REST | inhaled humidifier
90
What is the most common virus that causes Non-suppurative sialadenitis?
MUMPS
91
What bacteria typically causes suppurative sialadenitis?
Staph aureus
92
Which salivary duct most commonly is inflammed?
parotid duct
93
What are the clinical manifestations of bacterial suppurative sialadenitis?
Sudden onset of pain, fever, and chills Unilateral Firm and tender Expression of pus
94
How do we diagnose sialadenitis?
Physical exam MUMPS titer -RT PCR or serology if indicated HIV RNA if indicated If unclear or unimproved: Ultrasound CT face/neck Sialadenoscopy
95
How do we treat bacterial sialadenitis?
``` Paraenteral or oral antibiotics --> nafcillin, dicloxacillin, Augmentin Massage of duct Warm compresses Sialagogues Surgical drainage if abscess develops ```
96
What is chronic or recurrent sialadenitis?
Caused by obstruction (stone or stricture of duct) Repeated episodes of pain, swelling, and recurrent infections Swollen or firm gland; imaging revels calculus of dilated ducts Treat with hydration, gland massage, sialedonscopy, or surgery and antibiotic
97
What is neoplasm sialadenitis?
Benign or malignant Painless, firm, slow growing Imaging; CT or MRI; FNA Surgical removal of gland
98
What is autoimmune sialadenitis?
Caused by Sjogren's Gradual onset swelling bilateral parotid or submandibular Lab work specific to Sjogren's Supportive treatment
99
What is parotitis?
Acute-onset of parotid swelling lasting about 2 days Parmyxoviral disease spread by respiratory routes like saliva, droplets, and fomites
100
What is parotitis caused by?
exposure to MUMPS about 2-3 weeks before symptom onset
101
Who are most effeced by parotitis?
Children but college students are now being seen with it due to waning immunity to vaccines
102
What are the clinical manifestations of parotitis?
Bilateral parotid gland edema Flu like prodrome 48 hours before Unilateral testicular swelling and tenderness
103
What are the complications of parotitis?
Deafness Orchitis Meningitis Fetal congenital abnormalities
104
How do we treat parotitis?
``` Supprtive care: Bed rest Hydration Sialagogues Analgesia warm or cold compresses on parotid Testicular pain is treated with scrotal sling ```
105
What are cancers of the oral cavity associated with?
Ulcers or masses that DO NOT HEAL
106
What accounts for 80% of Squamous cell carcinoma of the head and neck?
Tobacco and Alcohol use
107
What is aphthous stomatitis?
Canker sore Painful oral lesion that often reoccurs
108
What is the most common acute oral lesion?
Aphthous Stomatitis
109
When do aphthous stomatitis usually develop?
First during adolescence and will wane with increasing age
110
Where does aphthous stomatitis usually occur?
in middle east and south asia
111
What type of aphthous stomatitis is most commoN?
simple aphthous
112
What is simple aphthous (Mikulicz)?
Several episodes a year May be 1 sore to several at a time They can last up to 14 days Limited only to oral mucosa
113
What is a complex aphthous?
``` Can be oral or genital More numerous lesions will occur Lesions are > 1 cm Takes 4-6 weeks to resolve So frequent that patients almost always have them ```
114
What are aphthous stomatitis caused by?
Multifactorial causes that are often unknown Immune dysregulation Exaggerated proinflammatory process Weak anti-inflammatory response Possibel genetic predisposition Certain foods can exacerbate them May be seen in celiac disease, IBD, or Crohn's Conditions that cause decrease in mucosal thickening Use of antimetabolites such as methotrexate for RA Vitamin B12, folic acid, or iron deficiency Neutropenia of any cause
115
What are the risk factors of aphthous stomatitis?
``` Smoking cessation Familial tendency Trauma like dental cleaning Hormonal factors like progestin falling in luteal phase of menstrual cycle Emotional stres Food or drug hypersensitivity Immunodeficiency ```
116
What are the clinical manifestations of Aphthous stomatitis?
``` 1-5 can occur at one time Round to oval shape Clearly defined ulcers Erythematous rim Yellowish/whitish central space Small, usually 1-3 cm Painful ```
117
How do we treat aphthous stomatitis?
Oral hygiene with non-alcohol mouthwash and soft toothbrush Pain control--> viscous lidocaine 2% applied directly or swish and spit Diphenhydramine liquid swish and spit Dyclonine lozenges Topical steroids--> Dexamethasone elixir swish and spit Clobetasol gel Triamcinolone paste
118
How do we treat complex aphthous stomatitis?
Intralesional or oral glucocorticoids for recalcitrant lesions or severe disease: Colchicine Dapsone Pentoxifylline as bronchodilator and immunomodulator Thalidomide in HIV infected patients
119
What is oral leukoplakia?
Benign reactive process | Clinical significance depends on degree of and presence of dysplasia
120
What is the change that oral leukoplakia will progress to carcinoma in 10 years?
1-20%
121
Who most commonly gets oral leukoplakia?
Men more than women Those with HPV Smokeless tobacco users
122
What are the clinical manifestations of oral leukoplakia?
Leukplakic lesions that show up in trauma prone regions like the cheek and dorsum of tongue where mucosa is normally thicker Thin areas of mucosa like ventral tongue or retromolar triangle show more dysplasia Not painful Whitish grey lesions Flat Not well defined Can't scrape off easily
123
How do we treat oral leukoplakia?
Most won't need treatment but if they do, surgery, cryoprobe, or chemoprevention
124
What is oral hairy leukoplakia?
NOT premalignant EBV associated Occurs almost entirely in HIV affected patients
125
Who is Herpes simplex virus (HSV-1) most common in?
women
126
What are the characteristics of primary HSV-1 infection?
HIghly variable and usually severe and systemic
127
What are the characteristics of recurrent HSV-1 infection?
Common but typically less severe and more local
128
What are the clinical manifestations of HSV-1?
Herpetic gingivostomatitis Multiple oral vesicular lesions and erosions surrounded by erythematous base Painful Prodromal of signs and burning, tingling, and pain will occur 24 hours prior to outbreak
129
Where do recurrent outbreaks of HSV-1 usually occur?
on lip borders
130
What are the symptoms that young children infected with HSV-1 will have?
Fever LAD Drooling Decreased oral intake
131
Where will sores be located in primary herpetic gingivostomatitis?
Inside of mouth
132
Where will sores be located in recurrent herpetic gingivostomatitis?
On outside of mouth
133
What are the risk factors for HSV-1?
Sunlight exposure Stress Trauma
134
What labs could you get to confirm HSV-1?
Tzanck smear, immunofluorescent smear or viral culture
135
How do we treat HSV-1?
Systemic antiviral --> Acyclovir, valacyclovir, or Famciclovir Swish and spit miracle mouthwash Supportive care Popsicles for kids
136
What is oral candida?
Common local infection involving oropharyngeal and esophageal mucous membranes
137
Who most commonly gets oral candida?
``` Young infants Older adults who wear dentures Those on antibiotics Those on chemotherapy Those on radiation of head and neck Those that are immunodeficient Those that have inhaled corticosteroids Those with xerostomia ```
138
What is oral candida caused by?
Candida albicans
139
What is pseudomembranous oral candida?
White plaques on buccal mucosa, palate, tongue, and oropharynx
140
What is atrophic oral candida?
Found around upper dentures and appear as erythema without papules
141
What are the clinical manifestations of oral candida?
``` Asymptomatic Dry mouth Loss of taste Pain with swallowing or eating White plaques on buccal mucosa, palate, or tongue Erythema without placques in denture wearers Painful swallowing if esophageal Beefy, red tongue with denture wearers Angula chelitis Painful fissuring ```
142
How do we treat oral candida in healthy patients?
Local therapy Nystatin suspension swish and swallow Clotimazole troches Miconazole buccal tabs
143
How do we treat oral candida in immunocompromised patients?
Diflucan PO
144
What structures are in the oropharynx?
Posterior 1/3rd of tongue Soft palate Lateral and posterior walls of throat Tonsils
145
What are the regions of the throat?
Nasopharynx Oral cavity Oropharynx Larynx
146
What are malignant neoplasms of head and neck?
Epithelial carcinomas of head and neck that arise from mucosal surfaces and are overwhelmingly Squamous cell carcinomca
147
What are anterior cancers of head and neck caused by?
Tobacco and alcohol
148
What are posterior cancers of head and neck caused by?
HPV 16 and 18
149
What are anterior cancers of head and neck associated with?
nonhealing ulcers or masses | Dental changes or poorly fitting dentures
150
WHo have a 3-8X greater risk of developing oral cancer?
moderate to heavy drinkers
151
Who has a 30X greater risk for oral cancers?
extremely heavy drinkers
152
Who has a 100X greater risk for oral cancers?
Heavy smokers and heavy drinkers
153
Who has a 5-9X greater risk for oral cancers?
Smokers
154
Who has a 17X greater risk for oral cancers?
heavy smokers
155
What are the risk factors for oral cancers?
Smoking Alcohol abuse HPV infection EBV infection
156
Who most commonly get oral cancers?
males
157
Who do HPV related oral cancers occur in?
younger patients usually in their 40s
158
What are the clinical manifestations of posterior tongue cancers?
HPV 16 Does not produce visible lesions/discolorations There are no warning signs There will be erythema but no ulcers
159
What are the clinical manifestations of Oral cavity cancers?
Lesions present as exophytic, ulcerative, and often painful
160
What do 2/3rds of patients with primary tongue lesions also have?
nodal disease
161
What is oral cavity squamous cell carcinoma usually proceeded by?
Leukplakia Erythroplakia Speckled Erythroplakia
162
What is erythroplakia?
Red patch similar to leukoplakia except that is has erythematous components
163
What is speckled erythroplakia?
Combination of red and white freatures Fiery red patch taht cannot be identified clinically/pathologically as any other definable disease Will show evidence of high grade dysplasia, carcinoma in situ, or invasive SCC Lesions appear as red, velvety patho that is often demarcated Some lesions may have rough, granular surface
164
What are the clinical manifestations of oral cavity squamous cell carcinoma?
Painless can appear as ulcer without adjacent mucosal change Continued growth can result in a mass with raised, rolled borders Pain/tenderness often will develop but later in the disease
165
What is the most common site of oral squamous cell carcinoma?
Tongue
166
What is the second most common site of oral cavity squamous cell carcinoma?
Floor of mouth
167
Where do the vast majority of tongue lesions in OC-SCC occur?
lateral and ventrolateral aspects
168
Where does oralpharyngeal squamous cell carcinoma develop?
Tonsillar region and base of tongue
169
What are the clinical manifestations of oropharyngeal squamous cell carcinoma?
Appear as ulcerated mass, fullness, or irregular erythematous mucosal changes Presents at more advanced stage as it grows undetected and has higher propensity for metastasis Presene of neck mass Sore throat Dysphagia
170
What are the clinical manifestations of SCC with leukoplakia?
Rough, papillary patch of leukoplakia seen in retromolar trigone and soft palate Large size and nonhemogenous nature of lesions worrisome for malignancy Biopsy shows invasive SCC
171
What are symptoms of oral cavity cancers?
``` pain that will occur in stage 3 or 4 Otalgia Dysphagia Odynophagia Airway obstruction Neuropathies ```
172
What are the signs of oral cavity cancers?
``` Cervical LAD Cranial neuropathies Decreased tongue mobility Fistulas Skin involvement ```
173
Where can oral cancer occur in oral cavity?
``` lips tongue floor of mouth Maxillary alveolar ridge/hard palate Mandibular alveolar ridge Buccal vestibules ```
174
Where can oral cancer occur in oropharynx?
Tongue base Soft palate Palatine tonsils Posterior wall of pharynx
175
Where can oral cancer occur in hypopharynx?
Piriform sinuses and postcricoid area leading into esophagus below
176
Where can oral cancer occur in larynx?
Supraglottis (epiglottis and false vocal cords) | Cancers here will spread to lymph nodes early
177
Where can oral cancer occur in glottis?
true vocal cords | Presents with hoarseness
178
What are some later symptoms of oral cancer?
``` Bleeding Loosening of teeth Difficult wearing dentures Dysphagia Dysarthria Hoarseness Development of a neck mass ```
179
How do we figure the extent of oral cancers?
Contrast or noncontrast CT scan of neck and head
180
What are the three clinical groups for treatment of oral cancers?
Localized disease Locally or regionally advanced disease Recurrent and/or metastatic disease
181
How do we treat localized oral cancers?
Curative intent by either surgery or radiation
182
How do we treat locally or regionally advanced disease?
Curative intent but with combined modality therapy using: Surgery Radiation therapy chemotherapy
183
How do we treat recurrent and/or metastatic oral cancer?
Treated with palliative care | THis can't be cured so radiation and chemo just extend the patients life for a few months and relieve the pain
184
Which oral cancer has the best overall 3 year survival rate?
Those caused by HPV