Thoracolumbar Spine V- Persistent IDD Flashcards
Persistent IDD is aka as….?
Degenerative Disc Disease (DDD)
Age-related disc changes although NOT always due to age
With chronic or persistent IDD, disc changes are due to numerous ________ and allow herniations (_______ _______) to GRADUALLY develop over time
variables; nuclear migration
Persistent IDD is most common in what region?
Lumbar
With persistent IDD, only ___-____% are symptomatic
1-3
Persistent IDD is the source of pain in < ___% of LBP
5
Persistent IDD is most common in ___-____ yr. olds
30-50
95% of persistent IDD cases occurs at which vertebral levels?
L4-S1
Persistent IDD ____ Acute IDD
A. >
B. <
A.
Is persistent IDD or acute IDD more prevalent?
Persistent IDD
Etiology of persistent IDD:
Acute ____
Mixed findings with ____
______ strength
_______ lifestyle
IDD
age
Lower
Sedentary
With persistent IDD, why could lower strength be the cause?
Bc the local muscles become weak and then the global muscles have to take over and become overworked from “picking up the slack”
With persistent IDD, why could a sedentary lifestyle be the cause?
“You don’t use it, you lose it” They are not moving enough and too little stress on the spine, is just as bad as doing nothing
What are two additional etiologies of persistent IDD?
Heavier occupational lifting
Smoking
With the etiology of persistent IDD, genetics typically are associated with:
_____ IDD and with ____-______ _______changes in the cervical region
Lumbar; age-related disc
With the etiology of persistent IDD involving genetics, ___-____% of inheritance can be modified by diet and lifestyle
65-85
With persistent IDD, it is NOT caused by….
_______ loading/______ activities
________ driving
routine/ physical
prolonged
The pathogenesis of persistent IDD is ________ and has what kind of inflammation?
gradual; persistent
With persistent inflammation, there is an in-growth of _______ fibers from _____IDD healing and can lead to what kind of pain?
nociceptive
ACUTE
nociplastic
With persistent inflammation, it brings excessive and destructive proteins ( _______ ) and what likely enters the disc?
amyloidosis; low-grade infection
Persistent IDD pathogenesis (gradual):
____ GAGs and MORE ______ and dehydrated nucleus (more or less/ synovial or fibrotic)
MORE _____ disc that kills disc cells and limits ______ (base or acidic/inflammation or proliferation)
_______ disorganization (annular or endplate)
_______ and loss of cartilage at ____ _____ (thickening or thinning/ nucleus pulposus or end plates)
________ inflammation and fatty deposits in vertebra ( ______ )- (decreased or increased/ fibrotic or modic)
NOW _______ herniations and nuclear migration GRADUALLY develop (per Miller)
(acute or persistent)
Less; fibrotic
acidic; proliferation
annular
Thinning; end plates
Increased; modic
persistent