Thoracic Cavity Development Flashcards

1
Q

What is the intraembryonic coelom?

A

The primordium of embryonic body cavities

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2
Q

Where does the horseshoe shaped cavity develop from?

A

The lateral mesoderm

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3
Q

What does the cranial end of the intraembryonic coelom form?

A

Future pericardial cavity

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4
Q

What way does the cranial ends of the intraembryonic coelom fold?

A

Head fold, brings the pericardium and heart VENTROCAUDALLY, to get heart to its position ANTERIOR to the forgut

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5
Q

What do the caudal limbs of the intraembryonic coelom form?

A
  • Future pleural and peritoneal cavities

- results in a gut tube suspended b/w 2 layers of mesentary

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6
Q

When do the caudal limbs lose connection with the extraembryonic coelom? Why?

A
  • 10th week of development

- developing intestines return to the body cavity

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7
Q

In what direction do the caudal limbs fold?

A
  • folds in the horizontal plane

- brings two caudal limbs VENTRALLY, and fuses to form the peritoneal cavity

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8
Q

What is mesentary?

A

Double layer of peritoneum that extends from abdominal wall

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9
Q

Dorsal mesentary

A

permanent structure, persists in entire body

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10
Q

Ventral mesentary

A

anything attached to the liver, remains attached to the caudal part of the foregut

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11
Q

What is the function of the mesentary?

A

Divides the cavity into right and left halves; conveys blood vessels, nerves, and lymphatics to organs

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12
Q

What is the pericardioperitoneal canal?

A

Term for intraembryonic coelem after embryonic folding

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13
Q

Where is the pericardioperitonal canal located?

A
  • lateral to foregut

- dorsal to the septum transversum

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14
Q

What does the septum transversum develop into?

A

The central tendon of the thoracic diaphragm

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15
Q

What causes partitions to form in each pericardioperitoneal canal? What are these partitions/

A
  • Developing bronchial buds

Partitions = cranial ridges (pleuropericardial folds); caudal ridges (pleuroperitoneal folds)

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16
Q

What do the pleuropericardial membranes contain?

A
  • common cardinal veins

- phrenic nerve

17
Q

What is the function of the common cardinal veins?

A

drains the primordial venous system into the sinus venosus of the primordial heart

18
Q

Pleural cavities expand ventrally around the heart and splits the mesenchyme into what?

A

Thoracic wall and fibrous pericardium (contains the phrenic nerve)

19
Q

How and when is the primordial mediastinum formed?

A
  • The pleurocardial membranes fuse with the ventral mesenchyme
  • Occurs by the 7th week
20
Q

What happens in the 6th week of development to the pleuroperitoneal membranes?

A

The membranes extend VENTROMEDIALLY and fuse with the dorsal mesentary of the esophagus and septum transversum

(pleural and parietal cavities are separated)

21
Q

What assists the closure of the pleuroperitoneal membranes?

A

the migration of myoblasts into the pleuroperitoneal membrane

22
Q

What does the diaphragm develop from? (4)

A
  1. septum transversum
  2. pleuroperitoneal membranes
  3. dorsal mesentary of esophagus
  4. muscular ingrowth from lateral body walls
23
Q

Diaphragm innervation

A
  • myoblasts migrate into pleuroperitoneal membrances from 2-5 cervical myotomes and carry their nerves
  • nerves pierce pleuropericardial membranes
24
Q

Where is the phrenic nerve located?

A

On the fibrous pericardium

25
Q

What structures does the ventral mesentary become? (5)

A

Suspends:

  1. primordial liver
  2. primordial stomach
  3. proximal part of duodenum

Becomes:

  1. falciform ligament
  2. lesser omentum
  3. visceral peritoneum surrounding liver
26
Q

What do the somites L4-S3 become?

A

Lumbar plexus

27
Q

What do the somites C5-T1 become?

A

Brachial plexus

28
Q

What do the somites C3-5 become?

A

diaphragm

29
Q

How would a hypoplastic lung develop?

A

If the costodiaphragmatic space (pleural cavity) does not grow faster than the lung

30
Q

Congenital hiatal hernia

A

a. Esophagus in the stomach are in the thorax because the mediastinum in the diaphragm did not develop properly, causing weakness in the esophageal musculature

31
Q

What goes through the septum transversum?

A

SVC

32
Q

Posterolateral defect

A

Pleural peritoneal membrane on left side did not fuse with central tendon of diaphragm