Things you just need to know Flashcards
AKI definition
Creatinine > 26 umol/L within 48hrs
Creatinine > 1.5 x baseline
Decreased urine volume < 0.5 mL/kg/hr for 6 hrs
AAA screening recommendations
Invitation to screening at 65 y/o
Normal - no rescan
3-5cm - rescan every 6 months
>5cm - rescan every 3 months
CHA2DS2-Vasc score
Congestive HF 1 HTN 1 Age >75 2 DM 1 Stroke/TIA 2 Vascular disease 1 Age 65-74 1 Female sex 1
Asthma attack
ABCDE resus
High flow O2
Salbutamol nebs (5mg, initially continuous then 2-4 hourly)
Ipratropium bromide (0.5 mg QDS
Steroid therapy (100-200 mg hydrocortisone followed by 40 mg oral prednisolone for 5-7 days)
If no improvement, IV magnesium sulphate, IV aminophylline, IV salbutamol)
Discharge when PEFR >75% predicted and stable for 24 hrs
Chronic asthma management
- Inhaled SABA prn (e.g. salbutamol)
- 1 + regular ICS (e.g. beclomethasone)
- 2 + LABA, then increase steroid dose
- Increase inhaled steroid dose, add leukotriene antagonist/theophylline/oral BA
- Add regular oral steroids, maintain high-doses and seek specialist care
Calculating plasma osmolality
2Na + 2K + glucose + urea
Diagnosing diabetes
HbA1c 48mmol/mol (6.5%) or more
FBG >6.9 mol/L (>125 mg/dL)
RBG >11.1 mmol/L (>200 mg/dL)
OGTT >11.1 mmol/L (>200 mg/dL)
LP results: cloudy CSF, high neutrophils, low lymphocytes, high protein, low glucose
Bacterial meningitis
LP results: clear CSF, low neutrophils, high lymphocytes, high protein, normal glucose
Viral meningitis
LP results: fibrinous CSF, low neutrophils, high lymphocytes, high protein, low glucose
TB meningitis
Cerebellar signs
Dysdiadocokinesia Ataxia Nystagmus Intention tremor Speech changes Hyperreflexia
Bacterial meningitis
Gm +ve cocci, elderly
Streptococcus pneumoniae
Bacterial meningitis
Gm -ve diplococci
Neisseria meningitides
Bacterial meningitis
Cheese consumption
Alcoholic
Listeria monocytogenes
Bacterial meningitis
Child
Unvaccinated
Haemophilus influenzae
Bacterial meningitis
Neonate
Extended labour, infection in previous pregnancy
Group B streptococcus
Bacterial meningitis
Late neonatal infection
E coli
Bacterial meningitis
Chronic infection
Mycobacterium TB
Infective endocarditis buzzwords
Prosthetic valve Dental procedure New onset murmur Right heart Indwelling catheter
Bone marrow failure with Auer rods
Acute myeloid leukaemia
Bone marrow failure in children
Acute lymphoblastic leukaemia
Bone marrow failure with Philadelphia chromosome
Chronic myeloid leukaemia
Bone marrow failure with smear cells and warm agglutinins
Chronic lymphocytic leukaemia
Painless lymphadenopathy Reed-Sternberg cells Binucleate lymphocytes Pain after alcohol Single group of nodes
Hodgkin’s lymphoma
Painless lymphadenopathy
Multiple groups of nodes
Non-Hodgkin’s lymphoma
Bone marrow failure without splenomegaly
Ringed sideroblasts
Myelodysplasia
Bone marrow failure with massive splenomegaly
Dry bone tap
Myelofibrosis
Increased calcium, renal failure, anaemia, bone lesions
Bence-Jones proteins (dense band)
Multiple myeloma
Plethoric face, headache, aquagenic pruritis
Polycythaemia vera
Normal Sodium levels
135-145
Normal Potassium levels
3.5-4.5
Normal urea levels
2-7
Normal CRP
0.5-10
Normal Ca levels
2.2-2.6
Lung cancer
Male, smoker
Found central at proximal bronchi
Spreads locally with late mets
Squamous cell carcinoma
Lung cancer
Female, non-smoker
Peripheral
Early mets
Adenocarcinoma
Lung cancer Smoking Aggressive, early mets Found centrally in proximal bronchi Paraneoplastic syndromes (e.g. SiADH)
Small cell carcinoma
Lung cancer Male Gynaecomastia (beta HCG) Peripherally Late mets
Large cell carcinoma
Lung cancer Found in apex Horner's syndrome Hoarse voice Pancoast syndrome - wasting of arm muscles, pain, paraesthesia, paresis
Pancoast tumour
Paraneoplastic syndromes
SiADH Cushing syndrome Hypoglycaemia Hypercalcaemia Carcinoid syndrome Lambert-Eaton Myasthenia syndrome Acanthosis nigricans Dermatomyositis
Complications of AKI
Metabolic acidosis Hyperkalaemia Uraemia Fluid overload Hyperphosphataemia Hypocalcaemia HTN
Pre-renal causes of AKI
IMPAIRED PERFUSION Cardiac failure Sepsis Blood loss Dehydration Vascular occlusion
Renal causes of AKI
Glomerulonephritis
Small vessel vasculitis
Acute tubular necrosis - drugs, toxins, prolonged hypotension
Interstitial nephritis - drugs, toxins, inflammatory disease, infection
Post-renal causes of AKI
Urinary calculi Retroperitoneal fibrosis Benign prostatic enlargement Prostate cancer Cervical cancer Urethral stricture/valves
AKI with brown cell casts in urine
Acute tubular necrosis
AKI with white cell casts in urine, infective
Acute interstitial nephritis
Pyelonephritis
AKI with eosinophilia, immune/non-infective
Acute hypersensitivity
Hypoalbuminaemia
Oedema
Lipid abs
Proteinuria
Nephrotic syndorme - HOLP
Structural (nephrosis)
Proteinuria Haematuria Azotemia Red cell casts Oliguria HTN
Nephritic syndrome - PHAROH
Inflammation (nephritis)