Thin Layer Chromatography

Question 1

Component eluted first, what does this say about the compound’s acidity or basicity

Answer 1

Ibuprofen; more soluble w/solvent (w/o acidic, wako kasabot ani kang mam help), thus also acidic.

Question 2

Relative polarities of aspirin, paracetamol, ibuprofen

Answer 2

Para>aspirin>ibuprofen
Para- more polar due to more H-bond acceptors and donors

Question 3

why it is necessary to maintain saturated vapor atmosphere when developing chamber? What happens if not done?

Answer 3

Too much solvent would evaporate and not move the compounded further as needed. Movement is dependent to solvent.