Therapeutic Gasses Flashcards
List the Therapeutic Gasses
Air
Oxygen(O2)
Nitrogen (N2)
Mixed Gases ( Helium-Oxygen and Nitrogen Oxygen)
CNS Oxygen Toxicity
Increased production of oxygen free radicals are potentially toxic to cell membranes, enzymes, nucleic acids, and other cell constituents
Symptoms of CNS O2 Tox
Visual Disturbances Ear - Tinnitus, ringing, or roaring Nausea/vomiting Tingling/Twitching Irritability - confusion/dysphoria DIzziness Convulsions
Threshold levels of CNS O2 Tox
0-0.5 ATA = innocuous
0.5-2.0 ATA = exposure limited by pulmonary O2 tox
>2.0 ATA = exposures limited by CNS Tox
Phases of seizure
Tonic - 1 minute
Clonic - 3-4 minutes
Post-ictal - 5-30 mintues
Pulmonary O2 Tox
Risk of pulmonary O2 tox can occur at 0.6 ATA
Related to length of exposure
Symptoms may appear after 12-16 hours on 100% O2 on surface
Signs and Symptoms of Pulmonary O2 Tox
End-respiratory discomfort Substernal burning and severe pain on inspiration SOB Pulmonary Edema Paroxysmal cough
Acute Exudative Phase of Pulmonary O2 Tox
Edema
Intraalveolar hemorrhage
Destruction capillary endothelial cells and type I alveolar epithelial cell
Subacute proliferative phase of Pulmonary O2 Tox
Interstitial fibrosis
Hyperplasia of type II alveolar epithelial cells