Therapeutic Antibodies (FA 210) Flashcards
Digoxin Immune Fab
target & clinical use
Digoxin
Antidote for digoxin intoxication
Muromonab-CD3
target & clinical use
CD3
Prevent acute transplant rejection
Infliximab
target & clinical use
TNF-a
Crohn’s disease, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis
Adalimumab
target & clinical use
TNF-a
Crohn’s disease, rheumatoid arthritis, psoriatic arthritis
Abciximab
target & clinical use
Glycoprotein IIb/IIIa
Prevent cardiac ischemia in unstable angina and in patients treated with percutaneous coronary intervention
Trastuzumab (Herceptin)
target & clinical use
HER2
HER2-overexpressing breast cancer
Rituximab
target & clinical use
CD20
B-cell non-Hodgkin’s lymphoma
Omalizumab
target & clinical use
IgE
Additional line of treatment for severe asthma