Therapeutic And Dx Procedures Flashcards
ORAL Premedication dose regimen for IVP dye
- Predisone 50 mg PO 13, 7 and 1 hour prior to procedure
- Benadryl 50 mg 1 hour prior to procedure
NPO premedication for IV dye allergy:
- hydrocortisone 200 mg IV 13, 7, and 1 hour prior to procedure
- Benadryl 50 mg IV/IM 1 hour prior to procedure
NOTE: 40 mg methylprednisolone can be substituted for 200 mg hydrocortisone dose for dose
URGENT premedication protocol for IV dye allergy (emergent):
- Hydrocortisone 200 mg IV 5 hours and 1 hour prior to procedure
- Benadryl 50 mg PO (or IM or IV if pt cannot take PO) one hour prior to procedure
NOTE: methylprednisolone 40 mg IV can substitute hydrocortisone 200 mg, dose for dose
Which of the following are accepted characteristics of ‘modified’ ECT?
A. Anesthesia w/ muscle relaxants is used to facilitate ECT
B. A tonic-clonic seizure is induced
C. A seizure longer than 30 seconds is classified as a prolonged seizure
D. Is always effective
E. Can be performed unilaterally
A, B, E
Absolute contraindications to ECT include: A. MI in last 3 months B. Presence of cochlear implant C. Hx of epilepsy D. Presence of pacemaker E. Pregnancy
NONE are absolute contraindications - pheochromocytoma is ONLY ABSOLUTE contraindication
Common side effects of ECT include: A. Headache B. Confusion C. Myalgia D. Long bone fx E. Urinary incontinence
A. Headache
B. Confusion
Treating epileptics with anti-convulsants May increase seizure threshold, what does this mean for ECT?
May require higher energy
ECT will do what to ICP, CBF, cerebral O2 requirements, and glucose utilization?
INCREASE them
What will ECT do regarding the BBB?
Increase permeability
T/F: Headache, confusion, and transient memory loss are common in immediate post ECT treatment period?
TRUE
What 3 things can Tricyclic antidepressants cause?
- Postural hypotension In elderly
- Widening QRS complex
- Prolong QT interval
What can be precipitated by using indirectly acting sympathomimentic drugs?
Hypertensive crisis
Monamine oxidase inhibitors are found to do what with both direct & indirectly acting sympathomimetics? How long before ECT therapy should they be stopped?
A profound pressor effect and should be stopped at least 2 weeks prior to therapy
SSRIs interact with meperidine and tramadol and may cause what?
Serotonin Syndrome (hyper-relfexia, agitation and hyperthermia)
What are the 7 relative contraindications of ECT?
- MI within 3 mos
- CVA within 3 mos
- Incr. ICP or cerebral aneurysm
- Unstable fx or cerebral spine injury
- Pheochromocytoma?
- Uncontrolled cardiac failure or sever valve disease
- DVT
What is the preferred muscle relaxant and dose for ECT?
Succinylcholine dose 0.5-1.5 mg/kg
What can be used to prevent parasympathetic response of ECT and dose(2)?
- Glycopyrrolate (0.2 mg)
2. Atropine (0.4 mg)
What can be used to treat sympathetic response of ECT with dose (2)?
- Labetolol (0.3 mg/kg)
2. Esmolol (1 mg/kg)
What are the triggering agents for MH & what does having these mean in the office-based setting?
inhaled general anesthetics (desflurane, isoflurane, sevoflurane) and Succinylcholine
Must have Dantrolene available if using these agents (36 vials of Dantrolene or 3 vials of Ryanodex)
What is the initial dose of dantrolene?
2.5 mg/kg
What are the required monitors/therapies for anesthesia(6)?
- Supplemental O2
- Pulse ox
- EtCO2 with disconnect alarm
- EKG and NIBP
- Temperature
- Patient positioning
What can radiation exposure cause?
Leukemia & fetal abnormalities
What is yearly max radiation exposure A. Annually, B. Lifetime, C. Monthly for pregnant women?
Yearly = 50 mSv Lifetime = Age x 10 mSv Pregnant = 0.5 mSv/month
What are the 9 predisposing factors to adverse reactions from contrast media?
- Hx of bronchospasm
- Allergy
- Cardiac disease
- Hypovolemia
- Hematologic disease
- Renal dysfunction
- Extremes of age
- Anxiety
- Medications (beta blockers, aspirin, NSAIDs)
What are considered MILD reactions to contrast media? (5)
Nausea, warmth, headache, itchy rash, mild hives
What are considered SEVERE reactions to contrast media (9)?
- Vomiting
- Rigors
- Feeling faint
- Chest pain
- Severe hives
- Bronchospasm
- Dyspnea
- Arrhythmias
- Renal failure
What are considered LIFE THREATENING reactions to contrast media? (5)
- Glottic edema/bronchospasm
- Pulmonary edema
- Arrhythmias
- Cardia arrest
- Seizures/ unconsciousness
What is considered to predispose people to renal dysfunction due to IV contrast?
Preexisting renal dysfunction, especially dysfunction d/t diabetes
Administration of this medication can decrease nephrotoxicity d/t contrast media? What is the dosing?
Acetylcysteine
IV = 150 mg/kg x 1 hour —> 50 mg/kg x 4 hours —> 100 mg/kg x 16 hours
What can happen in non-insulin dependent on Metformin if given contrast media?
Life threatening lactic acidosis
What is the number 1 problem in providing anesthesia in CT?
Inaccessibility to the patient
Why is hearing protection mandatory in MRI?
> 90 dB
What is the MOST SIGNIFICANT risk for MRI?
What are some examples?
Ferrous objects
- shrapnel, vascular clips and shunts, wire spiral ETTs, pacemakers, ICDs, mechanical heart valves, recent sternal wires, implanted biological pumps, foreign ferrous intraocular objects, some tattoos
What type of sedation is NOT advised in MRI? Why?
Deep sedation is not advised because of decreased access to airway. If sedation greater than moderate sedation is needed, GA is advised
If a cardiac or respiratory arrest occurs in MRI, what is the first thing that should be done?
Move patient outside of MRI suite for resuscitation attempts d/t equipment incompatibility with the magnet
What type of anesthesia is typically requested for radiology RFA?
GA with ETT
What are 4 major anesthetic requirements with cerebral coiling?
- 2 large bore IVs
- Pre-induction a line
- Frequent ACT checks
- Smooth emergence
What is a normal ACT range? What is ACT with heparin usually?
Normal = 70-120 seconds
With heparin = 180 - 240 seconds
With gastroenterology cases, most require incremental propofol administration until the _________________ is gone, and then maintain
Eyelid reflex
When doing an ERCP which antispasmodic is typically asked for? Dose? What adverse reaction can it cause?
- Glucagon
- 0.2-0.5 mg IV/IM
- ST
What 4 medications should be avoided if sphincter of Oddi manometry is being performed in ERCP?
- Opioids
- Robinol
- Atropine
- Glucagon
Urgent/emergent ERCP patients may have significant comorbidities that include: (5)
- Acute cholangitis with septicemia
- Jaundice (liver dysfunction)
- Coagulopathy
- Esophageal varices
- Biliary stricture
What happens in a TIPS procedure?
Transjucular Intrahepatic Portosystemic Shunt = connects right and left portal vein to one of three hepatic veins —> decompress portal circulation in patients with portal HTN
Patients with Down Syndrome are commonly seen in anesthesia for dental surgery, what things should you be aware of?
- Cardiac abnormalities (conduction abnormalities & structural defects)
- R/O Atlanto-occipital dislocation
- Airway difficulties (macroglossia, hypoplastic maxilla, palatal abnormalities, mandibular protrusion)
What meds with doses are common to use in dental surgery?
- Ketamine IV 1-2 mg/kg; Orally 5-10 mg/kg; IM 2-4 mg/kg
2. Oral midazolam 1 mg IV q 2-3 mins (max 2.5 mg); oral = 0.5-0.7 mg/kg 30 mins prior
How does ECT typically affect non-insulin dependent diabetics vs. insulin dependent diabetics?
- Typically improves glucose levels in non-insulin dependent
- Causes hyperglycemia in insulin-dependent
What is the typical CV response after ECT?
Bradycardia (parasympathetic) followed by hypertension, tachycardia (sympathetic)
According to Levi what is an absolute contraindication to ECT?
Pheochromocytoma (no absolute contraindications according to other sources)
What is a good med for attenuating hemodynamic response and has anticonvulsant effects for ECT?
Propofol
What 2 meds can be used for ECT that control w/o affecting seizure duration
- Clonidine (3mcg/kg 30 mins prior to procedure)
2. Precedex (1 mg/kg over 10 mins)
What are the 2 most common causes of death due to ECT?
MI and arrhythmia
What side should BP cuff be placed for ECT?
OPPOSITE arm of the IV
What is the “goal” of ECT?
30-60 second seizure
What happens if a magnet is placed on pacemaker?
Asynchronous demand mode (DDD) —> paces at set rate of pacer with no sensing
**good for increase slow HR if pacer set to a faster rate
What happens if Paget placed on ICD/pacemaker?
Shuts off defibrillator, no effect on pacer
What % of arterial stenosis is considered hemodynamically significant for cardia cath?
50-70% of diameter
What frequently occurs after revascularization following cardiac cath?
Arrhythmias that need treatment
What dose of heparin is commonly given during cardiac cath, with what goal?
2500-5000 units IV; GOAL ACT > 300 seconds
What is commonly the dose for protamine?
1-1.3 mg/100 units heparin given
What are 3 things to monitor for after protamine administration? Due to what?
- Peripheral vasodilation
- Anaphylactic/oid reactions
- Pulmonary vasoconstriction crisis
Due to histamine release
What is a side effect of the platelet aggregate inhibitor abciximab?
Increased ACT dependent of heparin
What is NPO time of solids/non-clears for adults? Clears?
Solids = 6-8 hours (or NPO after midnight) Clears = 2-4 hours
What is NPO time for children > 36 months for solids/non-clears? Clears?
Solids = 6-8 hours
Clears 2-4 hours
What is NPO time for children 6-36 months for solids/non-clears? Clears?
Solids = 6 hours Clears = 2-4 hours
What is NPO time for children < 6 months for solids/non-clears? Clears?
Solids = 4-6 hours Clears = 2 hours
What Aldrete score does pt have to have in order to be d/c from hospital?
9
Choose the statement that BEST describes the anesthetic considerations for pts undergoing ECT?
A. Hypocarbia increases seizure duration
B. Pregnancy is an absolute contraindication
C. Lithium shortens the duration of action of succinylcholine
D. There is an initial increase in sympathetic tone followed by an increase in parasympathetic tone
A.
According to APEX, what is the “gold standard” med to use for anesthesia during ECT? Why?
Methohexital (dose 80 mg) a barbiturate
- use because it produces a rapid recovery and has NO effect on seizure duration
What conditions can increase seizure duration? (2)
Hyperventilation
Hypocapnia
What conditions can decrease seizure duration (3)?
Hypoventilation
Hypercarbia
Hypoxia
Which commonly used meds for ECT increase seizure duration? (4)
- Etomidate
- Ketamine
- Alfentanil + propofol
- Aminophylline
Which common meds for ECT DECREASE seizure duration? (5)
- Propofol
- Midazolam
- Lorazepam
- Fentanyl
- Lidocaine
Which commonly used meds for ECT have NO EFFECT on seizure duration?
- Methohexital (barbiturate - gold standard)
- Precedex (higher alpha 2 selectivity)
- Clonidine
- Esmolol
What does the use of lithium prolong regarding anesthesia during ECT?
Duration of action of succs and NDNMBs
Patients on MAOIs who receive indirect acting sympathomimetics can experience?
Hypertensive crisis
What are the 5 areas points are awarded for the Aldrete score?
- Activity (0-2)
- Respiration (0-2)
- Circulation (0-2)
- Consciousness (0-2)
- Oxygen saturation (0-2)
All of the following are assessed by the modified Aldrete scoring system EXCEPT? A. PONV B. Respiration quality C. Level of consciousness D. O2 saturation
A. PONV
List the different safety zones in MRI suite, the supervision required with examples:
- Public access = no supervision = hallway outside MRI suite
- Public access = minimal supervision = entrance to MRI suite
- Limited access = strict supervision = MRI control room
- Very limited access = strict supervision = MRI scanner room
What zone of MRI are ferrous objects NOT allowed in?
Zone 4
Lit 4 safe metals in MRI
- Stainless steel
- Titanium
- Aluminum
- Copper
What is rate of allergic reaction to contrast media?
< 1%