Local Anesthetics Flashcards
Max dose bupivacaine w/ and w/o Epi
Plain = 2.5 mg/kg (175 mg)
W/ Epi = 3 mg/kg (225 mg)
Max dose Dibucaine, plain and w/ Epi?
Plain = 1 mg/kg
Etidocaine max dose, plain and w/ Epi?
Plain = 4 mg/kg (300 mg)
W/ Epi = 5 mg/kg (400 mg)
Lidocaine max dose, plain and w/ epi?
Plain = 4.5 mg/kg (300 mg)
W/ Epi = 7 mg/kg (500 mg)
Mepivacaine max dose plain and with epi?
Plain = 4.5 mg/kg (300 mg)
W/ Epi = 7 mg/kg (500 mg)
Prilocaine max dose, plain and w/ Epi?
Plain = 6 mg/kg (500 mg)
W/ Epi = 9 mg/kg (600 mg)
Ropivacaine max dose plain and with Epi?
Plain = 2.5 mg/kg (200 mg)
W/ Epi = 2.5 mg/kg
Chloroprocaine max dose plain and w/ Epi?
Plain = 12 mg/kg (800 mg)
W/ Epi = 15 mg/kg (1000 mg)
Cocaine max dose?
Plain = 3 mg/kg
Procaine max dose plain and with epi?
Plain = 7 mg/kg (500 mg)
W/ Epi = 8 mg/kg (600 mg)
Tetracaine max dose plain and with Epi?
Plain = 1.5 mg/kg (100 mg)
W/ Epi = 2.5 mg/kg (200 mg)
Which 2 anesthetics have no vasodilator activity?
- Cocaine
2. Ropivacaine (only parenteral with vasoconstrictive activity)
Clonidine dose for epidural? How long dose it increase neuraxial anesthesia?
2 mcg/kg or 150 mcg
Increase tine from 1.8 to 5.3 hours
Clonidine dose for spinal?
How much time does it increase neuraxial anesthesia?
- 15 - 45 mcg
- 45 mcg increased time from170 to 215 mins
At what lidocaine dose is analgesia produced with no cardiopulmonary effects?
1-5 mcg/mL
At what lidocaine plasma concentration does Tinnitus, numbness of lips and tongue, skeletal muscle twitching, restlessness, vertigo, and blurred vision occur; along with hOtn and myocardial depression?
5-10 mcg/mL
At what lidocaine plasma concentration do seizures, loss of consciousness occur?
10 - 15 mcg/mL
At what lidocaine plasma concentration does coma and respiratory arrest occur?
15 - 25 mcg/mL
At what plasma concentration does cardiovascular collapse occur?
> 25 mcg/mL
