Theme 6b Cellular Recognition Flashcards
1
Q
Syngeneic
A
identical at all genetic loci
2
Q
Congenic
A
genetically identical except at a single genetic region.
3
Q
Where do most MHC amino acid differences occur in the molecule?
A
at the groove sites.
4
Q
MHC variability on viral disease
A
in HIV certain HLA-B haplotypes are associated with slow disease progression, while others are associated with worse clinical outcomes.