Theme 6- THE RESEARCH OF THE DIFFUSION THROUGH A PERMEABLE MEMBRANE Flashcards
What is Fick’s 1st law
J = - D (dc/dx);
where J is the diffusion flux - the number of molecules diffused per unit time through a unit area,
D (m2/s) is the diffusion coefficient,
dc/dx is a very small change of the concentration dc at a very small distance dx
What is Fick’s 2nd law
dc/dt = D(d2c/dx2), where dc/dt is the very small change in concentration
dc during a very short dt.
-The physical meaning of dc/dt is the rate of change of concentration as a function of time,
and d^2c/dx2 is the second derivative of concentration as a distance function.
-The transport of substances/molecules takes place only in the presence of a spatial gradient. -The direction of the gradient is taken to be positive from higher to lower concentration
Types of passive transport
Diffusion
Filtration
Osmosis
Functions of passive transport
Passive transport plays an important role in the normal functioning of cells, organs and tissues of organisms.
Diffusion
-The transfer of molecules from a place of high to a place of low concentration due to the thermal movement of molecules.
-The driving force is the difference between the concentration of molecules on either side of the membrane or the region of various concentrations.
Filtration
-The transfer of water molecules from a place of high to a place of low hydrostatic pressure.
-The driving force is the difference in hydrostatic pressures on the two sides of the membrane.
-The passage of water continues until the hydrostatic pressures equalize.
-The hydrostatic pressure P is created by a water column of height h and is measured in Pascals (Pa), atmospheres or mm of mercury: P=ρgh, where ρ is the density of water, g is the acceleration of free falling of the Earth.
Osmosis
-The transfer of water from a place with a lower to a place with a higher osmotic pressure.
-The driving force in osmosis is the difference in osmotic pressures on the two sides of the membrane.
-The passage of water continues until the osmotic pressures equalize.
-The osmotic pressure π is created if the membrane does not allow a certain type of molecules through its pores
What is a reflection coefficient
-To characterize the ability of the membranes to allow the passing of the molecules of the dissolved substance or of the solvent/water/, a “reflection coefficient” - σ is introduced.
-With a completely permeable membrane σ=0 i.e. the membrane allows all molecules to pass
through.
-Diffusion and filtration are possible