Theme 1- MATHEMATICAL AND PHYSICS-CHEMICAL METHODS APPLIED IN BIOPHYSICS Flashcards
What is biophysics useful for?
-Biophysics is used widely and intensively in Medicine.
-Almost all life science research and
development studies involve Biophysics.
-All Medical research, development and treatment approaches involve Biophysics
What is Biological Thermodynamics?
A science that explains the nature and general laws of thermodynamic processes occurring in living organisms as nonequilibrium thermodynamic systems that convert the energy of the Sun and food into other types of energy
What is the importance of biophysics and mathematical methods of biophysics for medicine
-One aspect of this application is the creation of mathematical models of various disease processes, considering the interactions between the different components of the complex
biological system that underlies the processes inside the human organism.
-These researches hope to increase our understanding of the disease’s onset and how it progresses.
-Secondly, one hopes that the mathematical analysis of the available treatment strategies will enable one to identify one that is optimal in each situation
Examples of when doctors might use mathematical methods of biophysics
-Calculating medication dosages
-Interpreting medical research
-Tomography scans and X-rays
-Surgical operations
-Predicting medical outcomes
-Calculating medication dosages
Other specifical application of mathematical methods in medicine
-Maths allows us to describe how molecules move in and out of cells, how bacteria shuttle through blood vessels, how drugs get broken down in the body and many other physiological processes.
-Studying the geometry, topology and other physical characteristics of DNA,
proteins and cellular structures have shed light on their functions and on approaches for enhancing or disrupting those functions.
-Math helps medical scientists design their experiments, including clinical trials,
so they result in meaningful data of statistical significance
Power operations key ideas
1) Any base number raised to the power of 1 is the base itself
2) Any base number raised to the power of 0 equals 1
3) Powers can be simplified if they are multiplied or divided and have the same base
4) Powers of powers are multiplied
5) A negative power indicates a reciprocal
Logarithms
-Used to find an unknown power/exponent
-The general rule is;
N= b^x => logb(N) = x
Logarithmical scale of the acidity of solutions
A special scale called pH has been developed to measure acidity and is simply the “negative index” of the above scale
Natural logarithm
-The natural logarithm of a number is its logarithm the base of the mathematical constant, e which is an irrational and transcendental number approximately equal to 2.718281828459
-The natural logarithm of x is the power to which e would have to
be raised to equal x.
The natural logarithm has the following mathematical properties
In(1) = 0
In(e) = 1
In(xy) = In(x) + In(y) for x>0 and y>0
In(x/y) = In(x) - In(y)
In(x^y) = yInx for x>0