Thema 1 Flashcards

1
Q

granulocytes indicate

A

acute inflammatory proces

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2
Q

lymfocytes indicate

A

chronic inflammatory process

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3
Q

B-cells defend against

A

extracellular pathogens

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4
Q

T-cells defend against

A

intracellular pathogens

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5
Q

phases of B-cell development

A
  1. repertoire assembly
  2. negative selection
  3. positive selection
  4. searching for infection
  5. finding infection
  6. attacking infection
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6
Q

CD8 T-cells

A
Mass destructors
binds to MHC class I
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7
Q

CD4 T- cells

A
helper cells
Binds to MHC class II
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8
Q

T-cell activation by

A

antigen presenting cells (MHC)

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9
Q

MHC class I

A

HLA A,B and C
binds to CD8
presents intracellular proteins

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10
Q

MHC class II

A

HLA DR, DQ etc.
binds to CD4
presents extracellular peptides

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11
Q

T-cell independant antigens

A
no B cell-memory
no class switching (only IgM)
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12
Q

IgG

A

can pass placenta

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13
Q

IgA

A

can cross epithelium (is a dimer)
is in breast milk
mucosal glands (guts)

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14
Q

IgM

A

is what causes ABO system

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15
Q

IgE

A

all epithelial lining

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16
Q

apoptosis

A

includes decrease in cell size and fracturing

17
Q

necrosis

A

includes increase in cell size