Stack 4 Flashcards
1
Q
Calcineurin inhibitors
A
cyclosporin + tacrolimus
inhibit cytokine production (IL-2)
2
Q
side effects cyclosporin
A
renal insufficiency
neurotoxicity
hirsutism (hair growth)
3
Q
side effects tacrolimus
A
renal insufficiency
diabetes (especially post-transplant)
dyslipidemia
hypomagnesia/hyperkalemia
4
Q
corticosteroids
A
bind to nuclear receptor
stimulate expression of anti-inflammators and inhibits pro-inflammators
side-effects: hypertension
5
Q
side effects glucosteroids
A
moon- face (Cushing’s disease)
buffalo-hip
diabetes
6
Q
Cushing’s disease
A
too much steroids symptoms: osteoporosis obesity hypertension psychiatric symptoms moonface and buffalo hips
7
Q
Addison’s disease
A
too little steroids symptoms: nausea headache joint pain fever hypotension
