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Infectious disease > The uses of antibiotics > Flashcards

The uses of antibiotics Flashcards

1
Q

What are the main uses of benzylpenicillin

A
  • soft tissue
  • Pneumococcal
  • Meningococcal
  • gonorrhoea
  • Syphilis infection
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2
Q

What do benzyl penacillins act agains?

A
  • Streptococci
  • Neisseria
  • Spirochetes
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3
Q

What are the main uses of amoxicillin?

A
  • UTI

- RTI

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4
Q

What does amxacillin act against?

A

Broad spectrum, but resistnce common

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5
Q

What is the main use of flucoxacillin?

A

S. aureus

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6
Q

What is the main use of co-amoxiclav?

A
  • UTI
  • RTI
  • Soft tissue infections
  • Surgical wound infections
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7
Q

What does co-amoxiclav act against?

A

broad spectrum, including anaerobes

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8
Q

What is the main use ofpiperacillin/ tazobactam?

A

Neutropenic sepsis

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9
Q

What does piperacillin/ tazobactam act against?

A

Broad spectrum, including pseudomonas, anaerobes

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10
Q

What is the main use of cefradine (1st gen)?

A
  • UTI
  • Soft tissue
  • Infection
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11
Q

What does cefradine (1st gen) work against?

A
  • Broad spectum

- resistance +

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12
Q

What is the main use of cefuroxime (2nd gen)?

A
  • UTI
  • RTI
  • Surgical prohylaxis
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13
Q

What does cefuroxime (2nd gen) work against?

A

Broad spectrum

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14
Q

What is the main use of ceftriaxone/ cefotaxime (3rd gen)?

A
  • Hospital infections e.g. bacteraemia
  • pneumonia
  • Abdo. sepsis
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15
Q

What does ceftriaxone/ cefotaxime (3rd gen) work against?

A

Broad spectrum especially good against gram negative bacilli

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16
Q

What is the main use of ceftazidime (3rd gen)?

A

Pseudomonal infections in hospital and in cycstic fibrosis

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17
Q

What does ceftazidime (3rd gen) work against?

A

Life ceftriaxone but also active against pseudonomas

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18
Q

What is the main use of ceftaroline/ ceftobipirole (4th gen)?

A
  • Liscensed skin and soft tissue infection

- Endocarditis resistant to other treatment

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19
Q

What are the main uses of gentamicin?

A

Serous gram negative infections e.g. bacteraemia, endocarditis, neutropaenic sepsis

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20
Q

What does gentamicin act against?

A

Gram-negative bacilli

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21
Q

What are the main uses of clarithromycin?

A
  • Resp infection
  • Sodt tissue infection (if penicillin allergic)
  • STD
22
Q

What does clarythromycin act aginst?

A
  • Streptococci
  • Staphylococci
  • Mycoplasma
  • Chlamydia
  • Legionella
23
Q

What are the main uses of erythromycin?

A
  • Resp infection
  • Sodt tissue infection (if penicillin allergic)
  • STD
24
Q

What does erythromycin act aginst?

A
  • Streptococci
  • Staphylococci
  • Mycoplasma
  • Chlamydia
  • Legionella
25
Q

What are the main uses of azithromycin?

A

Chlamydia

26
Q

What does azithromycin act aginst?

A

Better for gram negative e.g. haemophilus, chlamydia

27
Q

What are the main uses of ciprofloxacin?

A
  • Complicated UTI
  • Complicated hospital aquired pneumonia
  • Some GI infections
28
Q

What does ciprofloxacin act aginst?

A

Gram-negative bacilli, including psuedomonas, some activity against staphylococci and streptococci

29
Q

What are the main uses of levofloxacin/ moxifloxacin?

A

2nd or 3rd line agent for pneumonia

30
Q

What does levofloxacin/ moxifloxacin act aginst?

A
  • Enhanced activity against staphylococci/ streptococci, less against psuedonomas
  • Active against pneumococcus, mycoplasma, chlamydia, legionella
31
Q

What are the main uses of vancomycin?

A
  • MRSA
  • Oatients allerfic to pennicillin
  • C. dif.
32
Q

What does vancomycin act aginst?

A

gram-positive bacteria only (staph and strep)

33
Q

What are the main uses of trimethoprim?

A
  • UTI
  • Resp infection
  • MRSA
34
Q

What does trimethoprim act aginst?

A
  • Some gram negative bacilli

- Some activity against staph. and strep.

35
Q

What are the main uses of co-trimoxazole?

A
  • Respiratory infection

- PCP

36
Q

What does co-trimoxazole act aginst?

A
  • Broad spectrum

- Pneumocystis jiroveci

37
Q

What are the main uses of clindamycin?

A
  • soft tissue infection

- Gangrene

38
Q

What does clindamycin act aginst?

A
  • Streptococci
  • Staphylococci
  • Anaerobes
39
Q

What are the main uses of teracycline/ doxacycline?

A
  • Q fever
  • Brucellosis
  • Chlamydia
  • Atypical pneumonia
  • MRSA
40
Q

What does teracycline/ doxacycline act aginst?

A
  • Strep.
  • Staph.
  • Chlamydia
  • Rickettsiae
  • Brucella
41
Q

What are the main uses of rifampicin?

A
  • TB
  • MRSA
  • Meningococcal prophylaxis
  • Complicated staph. infections
42
Q

What does rifampicin act aginst?

A
  • Mycobacteria
  • Meningococcus
  • Staph.
43
Q

What are the main uses of meropenem?

A

2nd or 3rd line for hospial infections

44
Q

What does meropenem act aginst?

A

broad spectrum including anaerobes, pseudomonas

45
Q

What does metronidazole act against?

A
  • Anaerobes

- Protasoa e.g. giardia

46
Q

What are the main uses of linezolid?

A

2nd line agent for MSSA, MRSA, VRE

47
Q

What are the main uses of metronidazole?

A
  • Surgical infections
  • Giardiasis
  • Amoebiasis
  • Trichomonal infections
48
Q

What does linezolid act against?

A

gram positive bacteria only (staph., strep, enterococci)

49
Q

What does daptomycin act against?

A

gram positive bacteria only (staph., strep, enterococci)

50
Q

What are the main uses of daptomycin?

A

2nd line agent for MSSA, MRSA, VRE

51
Q

What does tigecycine act against?

A

Very broad spectrum including: MRSA, ESBL, anaerobes

52
Q

What are the main uses of tigecycline?

A
  • 3rd line intra-abdominal sepsis

- Sodt tissue infection

Infectious disease (13 decks)

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