The Thyroid Gland Flashcards
Thyroid hormone is made primarily of the trace element _____.
Iodine
What are the three major binding proteins?
Thyroxine-binding globulin (TBG), thyroxine-binding prealbumin (TBPA), and albumin.
What is the most useful test in assessing thyroid function?
TSH.
How are serum T4 & T3 levels measured?
Radioimmunoassy (RIA) & Chemiluminometric assay.
What cell types secrete thyroglobulin?
Thyroid follicular cells.
Hypothyroidism is defined as what?
Low free T4 and normal/high TSH.
The most common cause of hypothyroidism is what?
Chronic lymphocytic thyroiditis (Hashimoto’s thyroiditis).
How is TPO antibody affected by lymphocytic thyroiditis?
Positive in most patients.
Transient hypothyroidism is associated with what?
Inflammation of the thyroid gland.
How is hypothyroidism treated?
Thyroid hormone replacement therapy (Levothyroxine [T4]).
Thyrotoxicosis can be the result of what?
Excessive thyroid hormone ingestion.
What disease is the most common cause of thyrotoxicosis?
Graves’ Disease
How does Graves’ Disease affect free T4, free T3, & TSH?
High FT3 and/or FT4
Low or undetectable TSH.
