The Skeletal System (Exam 2) Flashcards
Functions of the skeletal system
- Support (attachment for soft tissue and organs)
- Storage (lipid in yellow matter, Ca)
- Blood Cell Production (all BC in red bone marrow)
- Protection
- Movement
What type of tissue is bone?
supporting connective
What are bone cells called?
osteocytes
What salt is dissolved into the matrix of bone tissue?
Calcium phosphate
What form is calcium phosphate in for bone? (what is bone mineral?)
Hydroxyapatite
What are four general shapes of bone?
- Long
- Short
- Flat
- Irregular
General characteristics of a long bone
longer than they are wide (humerus ex)
General characteristics of a short bone
about as wide as they are long
example of a short bone
carpals
General characteristics of a flat bone
broad like scapula
General characteristics of an irregular bone
complex in shape
example of an irregular bone
vertebra
what are the three parts of a long bone?
Two epiphyses and a diaphysis
Describe the diaphysis
- central shaft of long bone
- hollow (marrow cavity)
Describe epiphysis
- end caps of bone
- covered with articulate cartilage
Where is bone marrow located?
marrow cavity
what composes articulate cartilage and what is its function?
hyaline cartilage; prevent damage at articulation
what bone tissue composes the diaphysis?
compact bone
what is another name for spongy bone?
cancellous bone
where is cancellous bone found?
in epiphysis, in middle cavity
describe the composition of cancellous bone
projections of bone separated by space
what is the outer covering of bone?
periosteum
what lines the marrow cavity and spongy bone?
endosteum
describe the two layers of the periosteum
fibrous outer layer, cellular inner layer (membrane)
name for bone cells
osteocytes
where are osteocytes located?
lacunae
where are lacunae found?
between sheets of lamellae
what are lamellae?
sheets of matrix
what are canaliculi and what do they do?
small channels that run through the matrix and connect lacunae to blood supply
what is an osteon?
repeating functional unit of compact bone that run parallel to its long axis
what is the system called describing osteons?
Harversian system
describe the structure of an osteon
osteon made of concentric circles of lamellae that surround a central canal
what is the purpose of the central canal?
it has blood vessels in it
perforating canals
allow for blood vessels in the central canal to be linked to other vessels
Compact bone covers______
all surfaces other than the articulate surfaces
what is compact bone’s axis of strength?
its long axis
describe the histology of cancellous bone
no osteons in spongy bone, trabeculae instead.
what are trabeculae?
rods of lamellae
where is spongy bone found?
epiphysis
spongy bone is _____ than compact bone
heavier (reduces work of muscles to move bone)
name three types of bone cells
- osteocytes
- osteoblasts
- osteoclasts
function of osteocytes
mature cells that maintain bone by recycling calcium salts
osteocytes recycle ______
calcium slats
process preformed by osteocytes
osteolysis- release of mineral through bone destruction
osteolysis
bone tissue destruction releasing minerals
what do osteoclasts release
acid and enzymes that break down bone
function of osteoblasts
carry out ossification
osteophysiological mechanism of releasing recourses
osteolysis
ossification
bone formation
general preview of generic ossification
cartilaginous formation at 6 weeks embryonic, replaced with bone through ossification
two types of ossification
- intramembranous
- endochondral ossification
what occurs during ossification?
calcification (can occur in other tissue too)
distinguishing characteristic of intramembranous ossification
no cartilage precursor
when does intramembranous ossification take place?
fetal development
overview of step of intramembranous ossification
- osteoblast differentiate from mesenchymal stem cells
- calcified matrix is developed
- ossification begins at ossification center
- spongy bone is remodeled into compact flat bones
_____ bones are mainly formed by intramembranous ossification
flat
generally, what is endochondral ossification
cartilaginous skeletal structures are replaced by true bone in a 5 step sequence
5 steps of endochondral ossification
- Chondrocytes enlarge, matrix calcifies (chondrocytes die)
- Bone formation starts at shaft surface (blood vessels invade perichondrium, new osteoblasts produce bone matrix)
- formation of primary ossification center as blood vessels enter shaft (bone develops to each end filling the bone with spongy bone)
- Osteoclasts break down spongy bone in middle to form marrow cavity (epiphyseal cartiliges continue to grow)
- secondary ossification centers form to fill epiphysis with spongy bone
bones grow in length from
epiphyseal cartilage
joint surfaces are covered in
articulate cartilage
bone growth accelerates at______ because of ____
puberty bc hormones
why do epiphyseal cartilages eventually close
osteoblasts produce faster than osteoclasts can break down
what is the epiphesial line
where epiphesial cartilage used to be
define appositional growth
enlargement in diameter of bone
mechanism of appositional growth
periosteum cells develop into osteoblasts and produce more matrix on outer surface while osteoclasts erode inside
what is enlarged during appositional growth?
marrow cavity
requirements for bone growth
- mineral supply
- Vitamin D3
- Vitamin A,C
- Growth, sex, thyroid and ca-balancing hormones
mineral required for bone growth
calcium salts
why is D3 important for bone growth
Ca intake
what is rickets
D3 deficiency
what do vitamins A C do for bone development
support osteoblasts
bone is _____ remolding via which 2 cells
remodling, osteoclast/osteoblast action
how fast is bone remodling in young adults
new skeleton every 5 years