The Renin Angiotensin-Aldosterone System Flashcards
what is the goal of the renin-angiotensin-aldosterone system?
to increase the blood pressure
what component of the RAAS is created and found in the liver that is activated by renin?
angiotensinogen
what is the role of ACE in the RAAS?
it converts angiotensin I to angiotensin II
what does ACE stand for?
angiotensin cleaving/converting enzyme
what are some of the roles of angiotensin II when activated in the RAAS?
- triggers the release of aldosterone
- increases blood volume
- increases systemic vascular resistance
- causes the release of ADH (antidiuretic hormone)
during RAAS activation, what gland releases aldosterone?
adrenal cortex
what is the role of aldosterone?
it causes the kidneys to keep sodium and water
during RAAS activation what gland releases antidiuretic hormone (ADH)?
the pituitary gland
what is the role of antidiuretic hormone (ADH) in RAAS activation?
it causes the kidneys to keep water
what cells release renin during RAAS activation?
juxta glomerular cells
macula dense cells are found in which part of the nephron?
the distal convoluted tubule
where are juxta glomerular cells found in the nephron?
afferent arterioles
how do ACE inhibitors lower blood pressure?
inhibit angiotensin converting enzyme (ACE), which disrupts production of angiotensin I (inactive) to angiotensin II (active)
