The process of synaptic transmission Flashcards
What is a synapse
The conjunction at the end of an axon and the dendrite or cell body of another
Includes:
The end of the presynaptic neuron
The membrane of the post synaptic neuron
The synaptic cleft
What does synaptic transmission include
Pre synaptic neuron
Post synaptic neuron
Synaptic cleft
Action potentials
Neurotransmitters
Synaptic vesicles
Receptors
Excitation
inhibition
1) Action potential
Action potential is the nerve impulses that travel down the neuron to the axon ready to be passed on.
Action potential reaches the synaptic vesicles in the pre syaptic terminal
2) Neurotransmitters
When the AP reaches the synaptic vessicles in the pre synaptic terminal, it causes them to release neurotransmitters into the synaptic cleft.
3) synaptic cleft
The neurotransmitters diffuse across the cleft and arrive at the post-synaptic membrane
4) post-synaptic receptors
Neurotransmitters bind to the specialised post synaptic receptors
5) effects
Either excitatory or inhibitory effects
EPSP or IPSP
6) EPSP
Increased voltage in the cell and more likely to reach the threshold of -55mv needed for a signal to be generated
7) IPSP
Decrease in voltage in the cell, therefore less likely to reach the threshold needed for a signal to be generated
8) Whether a signal is generated
depends on balance of EPSP and IPSP which the cell summates
10) Summation
chance the AP is generated can be increased if a singke synapse is stimulated frequently or if numrous synapses are stimulated at the same time