The process of synaptic transmission Flashcards

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1
Q

What is a synapse

A

The conjunction at the end of an axon and the dendrite or cell body of another

Includes:
The end of the presynaptic neuron
The membrane of the post synaptic neuron
The synaptic cleft

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2
Q

What does synaptic transmission include

A

Pre synaptic neuron
Post synaptic neuron
Synaptic cleft
Action potentials
Neurotransmitters
Synaptic vesicles
Receptors
Excitation
inhibition

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3
Q

1) Action potential

A

Action potential is the nerve impulses that travel down the neuron to the axon ready to be passed on.

Action potential reaches the synaptic vesicles in the pre syaptic terminal

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4
Q

2) Neurotransmitters

A

When the AP reaches the synaptic vessicles in the pre synaptic terminal, it causes them to release neurotransmitters into the synaptic cleft.

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5
Q

3) synaptic cleft

A

The neurotransmitters diffuse across the cleft and arrive at the post-synaptic membrane

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6
Q

4) post-synaptic receptors

A

Neurotransmitters bind to the specialised post synaptic receptors

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7
Q

5) effects

A

Either excitatory or inhibitory effects

EPSP or IPSP

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8
Q

6) EPSP

A

Increased voltage in the cell and more likely to reach the threshold of -55mv needed for a signal to be generated

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9
Q

7) IPSP

A

Decrease in voltage in the cell, therefore less likely to reach the threshold needed for a signal to be generated

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10
Q

8) Whether a signal is generated

A

depends on balance of EPSP and IPSP which the cell summates

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11
Q

10) Summation

A

chance the AP is generated can be increased if a singke synapse is stimulated frequently or if numrous synapses are stimulated at the same time

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