The Modern World - c.1900 - Present Day Flashcards
What had Britain and the world accepted about germs by 1900?
That they existed
That they caused a great deal of diseases
What had we not discovered by the start of 1900?
- How diseases are connected to our “pathways”
* Hereditary diseases
What further things were doctors interested in regarding the cause of illnesses?
Hereditary diseases
DNA
Lifestyle - Diet & Exercise
What did Archibald Garrod theorise in 1902?
Hereditary diseases - caused by missing information in the body’s chemical pathways
Who discovered DNA in 1953?
Rosalind Franklin - photographed it
James Watson and Francis Crick - published a paper proving the understood it
What project was launched in 1990?
Humane Genome Project
What does detailed understanding of DNA allow?
Exploration of hereditary diseases
Why do doctors take an interest in lifestyle factors like diet and exercise?
They have direct links to causes of illness - cancer and diabetes
What was the first “magic bullet” discovered in 1909?
Salvarsan 606 - The first chemical cure
What was discovered about prontosil in 1932?
It cured blood poisoning - deaths fell from 20% to 4.7%
Who were the three people involved in the creation of penicillin?
Alexander Fleming
Howard Florey and Ernst Chain - took Fleming’s research further - proven penicillin could kill infections in the body - gained US support for mass production of it
What was Streptomycin able to do in 1943 that people thought could never be done?
Cured TB - an extremely powerful antibiotic
How did Fleming discover the mould that can be used to create penicillin?
He noticed that mould had developed accidentally on a set of culture dishes being used to grow the staphylococci germ. The mould had created a bacteria-free circle around itself.
What actions did Florey and Chain take to make it manufacturable?
Proved it could kill infections inside the body.
What further vaccinations have been created during the 20th century?
1909 - Salvarsan, Syphillis 1932 - Prontosil - Blood Poisoning 1938 - M&B 693 - Pneumonia 1942 - Diphtheria 1943 - Streptomycin - TB 1950 - Whooping Cough 1961 - Tetanus