The Immune System Flashcards

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1
Q

What is the purpose of T helper (th) cells?

A

They help B cells make antibodies.

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2
Q

What is the purpose of cytotoxic T lymphocytes (CTL)?

A

They kill infected cells.

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3
Q

Define innate immunity.

A

Consists of non-specific components.

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4
Q

Define acquired immunity.

A

Requires recognition specificity to foreign (non-self) substances.

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5
Q

Adaptive and innate immunity depends upon what?

A

Leucocytes.

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6
Q

Innate immunity is mediated largely by what?

A

Granulocytes.

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7
Q

Adaptive immunity mediated by what?

A

Lymphocytes.

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8
Q

What are the three immune system tasks?

A
  1. Detection and inactivation of infectious agents or their toxins.
  2. Detection and killing of virus infected body cells.
  3. Detection and killing of cancer cells.
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9
Q

Define antigenic determinant.

A

A part of the protein which combines with an antibody or a specific receptor on a lymphocyte.

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10
Q

Define immunogen.

A

Any agent capable of inducing an immune response.

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11
Q

Define hapten.

A

Small molecules which could never induce an immune response when administered by themselves but which can when coupled to a carrier molecule.

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12
Q

Haptens have the property of antigenicity but not what?

A

Immunogenicity.

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13
Q

Define immunogenicity.

A

The ability to induce a humoral and/or cell mediated immune response.

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14
Q

Define antigenicity.

A

The ability to combine specifically with the final products of immunogenicity.

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15
Q

What are usually poorly immunogenic?

A

Nucleic acids.

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16
Q

Is a molecule more immunogenic if it’s larger or smaller?

A

Larger.

17
Q

Adjuvants may act through what three basic mechanisms?

A
  1. Enhance long term release of the antigen.
  2. Act as non-specific mediators.
  3. Enhance macrophage phagocytosis.