Principles Of Inheritance Flashcards

1
Q

Which Austrian monk carried out experiments using peas?

A

Gregor Mendel.

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2
Q

Define character.

A

Heritable feature.

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3
Q

Define trait.

A

Variant for a character.

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4
Q

Define phenotype.

A

Organisms traits.

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5
Q

Define genotype.

A

Genetic makeup.

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6
Q

Define F1.

A

First set of offspring.

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7
Q

Define F2.

A

Second set of offspring.

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8
Q

What is Mendel’s first law?

A

The two members of a gene pair segregate from each other in meiosis; each gamete has an equal probability of obtaining either member of the gene pair.

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9
Q

What is Mendel’s second law?

A

The law of independent assortment; unlinked or distantly linked segregating gene pairs assort independently at meiosis.

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10
Q

Who recognised that Mendel’s experiment reflects the behaviour of chromosomes during meiosis?

A

Sutton and Boveri.

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11
Q

The existence of genes can be inferred by observing what?

A

Standard progeny ratios in the descendants of matings between different phenotypes.

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12
Q

Discrete phenotypic difference in a character is often determined by what?

A

A difference in a single gene.

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13
Q

Define autosome.

A

A chromosome that is not an sex chromosome.

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14
Q

Define lethal allele (homozygous lethals).

A

Alleles that cause an organism to die only when present in homozygous condition.

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15
Q

Define penetrance.

A

The percentage of individuals with a given genotype who exhibit the phenotype associated with that genotype.

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16
Q

Define 100% penetrant.

A

Genotype always shows phenotype.

17
Q

Define expressivity.

A

Degree to which a particular genotype is expressed in the phenotype.

18
Q

Define complete penetrance.

A

Identical known genotypes yield 100% expected phenotype.

19
Q

Define constant expressivity.

A

Identical known genotypes with no expressivity effect yield 100% expected phenotype.

20
Q

Define incomplete penetrance with variable expressivity.

A

Identical known genotypes produce a broad range of phenotypes due to varying degrees of gene activation and expression.

21
Q

Define incomplete penetrance.

A

Identical known genotypes yield less than 100% expected phenotype.

22
Q

Define variable expressivity.

A

Identical known genotypes with an expressivity effect yield a range of phenotypes.

23
Q

Who carried out the experiment of inheritance in sweet peas involving flower colour?

A

Bateson and Punnett.

24
Q

Define propositus.

A

A member of a family who first comes to the attention of a geneticist.

25
Q

What is the most common monogenic disorder?

A

Cystic fibrosis.