The immune response Flashcards
defence mechanisms
physical and chemical, inflammation, specific immune response
the body’s own cells
self
foreign cells
non-self
cells identified as non-self
-pathogens
-abnormal body cells (cancer or pathogen-infected cells)
-toxins
-cells from other individuals
antigens
surface molecules used by the body to identify cells
what is found in phospholipid bilayer to identify cells
specific molecules on surface of cells that allow them to be identified. they are usually proteins such as glycoproteins (but can be glycolipids)
antigens - unique
antigens are unique to the microorganisms which allow cell-to-cell recognition
where are antigens found
-cell surface membranes, bacterial cell walls or surfaces of viruses
-some glycoproteins/lipids act as antigens
self antigens
produced by the organisms own body cells –> don’t stimulate immune response
non-self antigens
not produced by organisms own body cells –> stimulate an immune response
what is antigen variability due to
antigens present on surface change frequently due to genetic mutations
problems due to antigen variability
immune response is specific and no longer complementary to antigen
phagocytes produced and stored
bone marrow
phagocytes job
removing dead cells and invasive microorganisms
phagocytes specific or non-specific
non-specific immune response