The Heart: Gross Anatomy Flashcards

1
Q

Layers of the heart

A
  1. Endocardium:
    - simple squamous epithelium(endothelium) that lines all heart chambers and valves
    - function: reduces trauma to blood cells against heart walls
  2. Myocardium:
    - cardiac muscle thicker on left side
    - function: pumps blood within/from heart
  3. Pericardium:
    - external serous membrane
    - parietal pericardium
    - visceral pericardium or “epicardium”
    function: isolates/lubricates heart
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2
Q

Chambers

A
  1. Atria (L and R):
    - receiving chambers for incoming venous blood.
    - prenatal connection= foramen ovale (allows blood to bypass the lungs)
  2. Ventricles (L and R): pumping chambers of outgoing arterial blood
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3
Q

Major Associated Vessels

A
  1. Inferior Vena Cava:
    - vein entering lower right atrium that receives blood from lower extremities and abdomen
  2. Superior Vena Cava:
    - vein entering upper right atrium that receives blood from head and upper exttemities
  3. Pulmonary Artery:
    - from right ventricle branching to lungs
    - fetal connection with aorta = ductus arteriosus (changes to ligamentum arteriosus after birth)
  4. Pulmonary veins (4): from lungs to left atrium
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4
Q

Aorta:

A

-leaves left ventricle

  1. coronary vessels:
    - R and L coronary arteries are first branches of aorta, which supply oxygen to myocardium.
    - cardiac veins—->coronary sinus; return blood from myocardium to R atrium
  2. aortic arch:
    aortica arch—->thoracic aorta
    -possesses 3 major branches: brachiocephalic, L common carotid, L subclavian
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5
Q

Heart Valves

A
  1. prevent backflow(“regurgitation”)
  2. Atrioventricular:
    - R=tricuspid L=mitral
    - flaps restrained by chordae tendinae, connected to papillary muscles
  3. Semilunar:
    - R=pulmonary L=aortic
    - valves sealed by overlap of three cusps
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6
Q

Cardiac cycle

A
  1. atrial relaxation (blood enters both atria)
    ventricular contraction(systole) blood leaves ventricles
    -AV valves closing “Lub” sound
    - semilunar valves open
  2. atrial contraction (blood leaves both atria)
    ventricular relaxation (diastole) blood fills ventricles
    -AV valves open
    - semilunar valves closing “Dub” sound
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7
Q

Coordination and control of the heart:

A
  1. Pacemaker= sinoatrial (SA) node
    - Superior/posterior portion of right atrium that sets contractile rate for both atria
  2. Receiver= atrioventricular (AV) node
    - on lower interatrial septum
    - accepts electrical excitation from atria
  3. Transmitter=atrioventricular bundle
    - connected to AV node
    - spreads excitation through ventricular walls via the conduction myofibers(Purkinje fibers)
  4. heart rate
    - suppressed by parasympathetic nerves (vagus)
    - accelerated by sympathetic nerves (T-1 through T-5)
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8
Q

Arteries

A

Three tissue layers:

  1. tunica interna (intima):
    - simple squamous epithelium over thin layer of elastic connective tissue
  2. tunica media:
    - elastic fibers and circular smooth muscle
  3. tunica externa:
    - elastic and collagenous fibers
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9
Q

veins

A

Three tissue layers:

  1. tunica interna:
    - less connective tissue than arteries of similar size
  2. tunica media:
    - less smooth muscle than arteries
  3. tunica externa:
    - slightly thicker than arteries

~veins carry blood at lower pressures than arteries;collapsible
~venous valves: two endothelial flaps prevent back flow, especially in veins below heart

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10
Q

capillaries

A
  1. microscopic vessels carrying blood between arterioles and venules
  2. One cell layer (tunica interna):
    • simple squamous epithelium permits diffusion of O2/ CO2, nutrients, and wastes to/from adjacent tissue cells.
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11
Q

pulmonary circulation

A
  • circuit through the lungs for reoxygination of the blood and elimination of CO2
    1. capillary network surround alveoli pick up O2 and release CO2
    2. pulmonary veins:
  • two from both lungs
  • return oxygenated blood to left atrium
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12
Q

systemic circulation

A

-circuit to deliver oxygen/nutrients to all organs and return CO2 and waste products to the heart.

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13
Q

hepatic portal circulation

A
  1. portal vein:
    - receives venous blood from splenic vein, gastric vein, inferior mesenteric vein, superior mesenteric vein
    - circuit from organs of the digestive tract to the liver
    - stores, modifies, or detoxifies substances from g.i. tract and adds plasma proteins and glucose to blood
    - returns blood systemic circulation vie hepatic veins
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14
Q

plasma

A

-90% water
-cell nutrients, wastes, hormones, blood gases
-plasma proteins: confined to the bloodstream; produced in liver
~albumin
~globulins(alpha/beta/gamma)
~fibrinogen and prothrombin (coagulation)

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15
Q

RBC production (erythropoiesis)

A
  1. develop in red bone marrow
    hemocytoblast(stem cell)—>erythroblast(hemoglobin forming)—>reticulocyte(nucleus expelled)—>erythrocyte(mature RBC)
  2. RBC contain “hemoglobin”:
    - heme=red, iron containing pigment that carries O2
    - globin=protein portion that carries CO2
  3. RBC production stimulated by “erythropoietin”, a hormone from the kidney
  4. RBC destruction in liver or spleen:
    - macrophages phagocytize worn or damaged cells
    - globin returned to circulation
    - heme—> iron(recycled of restored) bilirubin (excreted in bile)
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16
Q

Leukocyte production

A
  1. granular types:
    - formed in red bone marrow
    - hemocytoblast–> myeloblasts–> eosinophils (combat parasitic infection)–> basophils (release anticoagulant)–> neutrophils (bacterial phagocytes)
  2. nongranular types:
    - originally from thymus or bone marrow at birth, then distributed to lymph tissues.
    - hemocytoblast–>monocytes (move outside capillaries as macrophages)–> lymphocytes (produce antibodies for immunity)
  3. thrombocyte production:
    - formed in red bone marrow
    - hemocytoblast–> megakaryocytes–> fragments=platelets (release agents for blood clotting)
17
Q

functions of blood

A
  1. O2 and CO2 transport and exchange
  2. nutrient and waste transport
  3. hormone transport
  4. thermoregulation
  5. antibody circulation/immunity
  6. coagulation
18
Q

blood disorders

A
  1. anemias: diminished capacity to transport oxygen via erythrocytes
    a. hemorrhagic anemia
    b. iron deficiency anemia
    c. pernicious anemia
    d. aplastic anemia
    e. sickle cell anemia
  2. polycythemia: excessive, immature erythrocytes
  3. leukemia: excessive immature or old leukocytes, cancer of lymph tissue or bone marrow
  4. hemophilia: bleeding disorder from inadequate levels of chemical clotting factors.