The global impact of HIV Flashcards

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1
Q

How many individuals are infected with HIV worldwide?

A

40 million

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2
Q

What are the major problems encountered in Africa with HIV?

A

high rates of co-infection with TB
MTCT
limited access to antiretroviral therapy

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3
Q

What public health/wider concerns are there with HIV?

A
depleted workforce/workforce needed to care for them
orphans
marginalised groups and stigma
cost
hospital services
national budget
gender inequality
TB
loss of income
carers
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4
Q

What percentage of HIV is in sub-saharan africa?

A

66%

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5
Q

Who is at most risk of HIV globally?

A

heterosexual women

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6
Q

Who is at most risk of HIV in the UK?

A

MSM

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7
Q

What are the three stages of the HIV epidemic?

A

Nascent
concentrated
generalised

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8
Q

What age group is most affected by HIV worldwide?

A

15-24 year olds

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9
Q

What were the UNAIDS targets for 2015?

A
  1. reduce sexual transmission by 50%
  2. reduce transmission by 50% among IVDUs
  3. Eliminate new HIV infections among children and reduce AIDS related maternal deaths
  4. reach 15mln people on antiretrovirals
  5. reduce TB deaths in people with HIV by 50%
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10
Q

by what percentage does condom use reduce HIV transmission?

A

80%

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11
Q

List ways to reduce sexual transmission of HIV

A

condoms
male circumcision
microbicidal gel
vaginal ring

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12
Q

List ways why circumcision works for HIV?

A
  1. keratinisation - so HIV cannot penetrate into the mucosa
  2. inner part of foreskin contains Langerhans cells which are prime targets for HIV
  3. ulcers occur on the foreskin
  4. foreskin may suffer inflammation or abrasions during sex,
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13
Q

What is the problem with vaginal rings and condoms?

A

people don’t use them

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14
Q

How can HIV spread by IVDUs be reduced?

A

needle exchange programmes

removal of compulsory drug detention centrea

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15
Q

What percentage decrease in the risk of transmission of HIV to a HIV - partner is there when the HIV + partner is on HAART?

A

96%

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16
Q

What is the main factor to prevent the risk of HIV transmission?

A

antiretrovirals

17
Q

What are the reasons why antiretrovirals may be hard to implement in poor countries?

A

awareness - need to know they have HIV and what it is
delivery
clinical services: staff, clinics, testing and monitoring
cost
adherence
efficacy
co-morbidities

18
Q

What is at the centre of access to all other HIV treatments?

A

HIV testing