the geriatric patient part 3 Flashcards
what is gerontology
Gerontology is the study of aging, including biologic, sociologic, and psychologic changes.
what is typically considered the age that is considered “old age”
age >65 because this determines eligibility for medicare insurance in the US
what are the top 15 causes of death in people >65
- diseases of the heart
- malignant neoplasms
- COVID-19
- cerebrovascular diseases
- alzheimer’s disease
- chronic lower respiratory disease.
- Diabetes mellitus
- accidents (unintentional injuries)
- nephritis, nephrotic syndrome and nephrosis
- influenza and pneumonia
- parkinson disease
- essential hypertension and hypertensive renal disease.
- septicemia
- chronic liver disease and cirrhosis
- pneumonitis due to solids and liquids
what is the pathological process of aging
the inevitable, irreversible decline in organ function that occurs over time even in the absence of injury, illness, environmental risks or poor lifestyle choices.
what are the most affected systems in the pathological process of aging
- CV
- renal
- CNS
occurs from inflamation, tumor growth, thrombosis, necrosis, fibrosis, atrophy, pathological hypertrophy, dysplasia or metaplasia.
Has abnormal or deleterious effect at the sub cellular, cellular, multicellular or organismal level
what are four things that clinicians should assure to NOT do when observing/treating elderly patients
- mistake pure aging for disease
- mistake disease for pure aging
- ignore the increased risk of adverse drug effects on weak link systems stressed by illness
- forget that older adults have multiple underlying disorders that accelerate the potential for harm
flip this for the chart that breaks down agings affects of physical and cognitive frailty
what does frail mean?
weak/delicate
what is frailty in elderly populations
A vicious cycle of declining energetics and reserves that leads to a progressive decline in health and function
what are the primary causes of physiologic decline at the molecular level
- biological mechanisms
- pathophysiologic biomarkers
- clinical presentation (cog and physical impairments
what are examples of biological mechanisms for physiologic decline
- mitochondrial dysfunction
- telomere shortening
- Stem cell exhaustion
- DNA damage
- DNA methylation
- impaired autophagy
- oxidative stress
- senescence
What are examples of pathophysiologic biomarkers
- inflammation
- weight loss
- poor endurance
- weakness
- neurodegeneration
- energy imbalance
- anabolic hormone deficit
What are the clinical presentation cognitive and physical impairments that occur in physiologic decline
- cognitive impairment
- reduced mobility
- slowness
- low physical activity
- depression
- impaired physical function
- multiple chronic diseases
- Loss of independence
what is the difference between homeostasis and homeostenosis
in homeostasis the body CAN recover from stress
in homeostenosis the body CANNOT recover from stress
what are presentation and diagnosis aging considerations for the elderly population
- atypical presentations of medical conditions
- older people may not have spiking fevers or elevated white blood cell counts with an infection
- heart disease may be silent
- Cognitive and affective disorders are common and may be undiagnosed in early stages
- Reversible and treatable conditions can be under-diagnosed and under-evaluated