the fluid mosaic model Flashcards
what did charles overtun propose in 1895
membranes are made of lipids. experiments in which he discovered similarities between membranes and lipids and that lipid-soluble molecules enter cells faster than other substances
what did irving langmuir propose in 1917
did experiments with oil and water
he published a paper proposing that lipid molecules form a monolayer on water, with phosphate group heads in contact with water whilst their fatty acid chain tails point away from the water
what did evert gorter and f.grendel propose in 1925
experiment with red blood cells, extracting all the lipid. they found that when spread out the surface area of the lipid is about twice the surface area of the cells. they suggest that membranes are made of a phospholipid bilayer.
what did hugh davson and james danielli propose
chemical analysis of membranes indicate the presense of large amounts of protein. they suggested that the phospholipid bilayer is sandwiched between layers of globular protein. their model was widely accepted
what did jonathan singer and garth nicolson propose in 1972
new evidence led them to propose that proteins are embedded within the phospholipid bilayer and are free to move around. their model was the fluid mosaic model.
