diffusion Flashcards

1
Q

why do cells need to receive raw material

A

for the biochemical reactions and processes that go on in cells to sustain life

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2
Q

what do cells make when they respire

A

ATP

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3
Q

what does ATP provide

A

cellular energy to drive biochemical reactions

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4
Q

what do cells need to respire

A

they need oxygen and glucose and need to remove the toxic metabolic ewaste products such as carbon dioxide.

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5
Q

what else do cells need to do apart from respiring

A

to export some of the molecules they make, such as enzymes, hormones or other signalling molecules

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6
Q

what does active and passive transport refer to

A

the exchange of substances between cells and their environment, or between membrane bound compartments within cells and the cell cytosol

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7
Q

what does all movement require

A

energy usually in the form of ATP

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8
Q

what does passive movement utilise

A

passive transport utilises energy from the natural motion of particles rather than the energy from another source. they do not use ATP

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9
Q

what is diffusion

A

the net movement of particles (atoms, molecules or ions) from a region of high concentration to a region of low concentration

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10
Q

what kind of process is diffusion

A

a passive process

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11
Q

at what point does diffusion continue to occur

A

until there is a concentration equilibrium between the two areas

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12
Q

why does diffusion happen

A

the particles in a gas or liquid have kinetic energy. this movement is random and an unequal distribution of particles eventually becomes an equal distribution.

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13
Q

what does equilibrium actually mean

A

it doesnt mean the particles stop moving, the movement is just equal in both directions

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14
Q

why is diffusion fast over short distances

A

particles move at high speeds which are constantly colliding which slows down their overall movement. so diffusion is faster when the pathway is shorter. as diffusion distance increases, the rate of diffusion slows down because more collisions take place

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15
Q

what is a concentration gradient

A

a difference in concentration. it goes from high to a low concentration

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16
Q

where does diffusion take place along the concentration gradient

A

DOWN the concentration gradient

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17
Q

what acts as a barrier in the membrane

A

the non polar, hydrophobic tails of phospholipid molecules.

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18
Q

if a molecule is small and less polar what does this mean

A

it will diffuse across the membrane easier and faster

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19
Q

when does simple diffusion take place

A

for small non polar molecules.

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20
Q

what types of molecules can easily pass through the lipid bilayer

A

small non polar molecules in a high concentration on one side of the membrane can easily pass through the bilayer. lipid soluble molecules and very small molecules can diffuse directly through the bilayer

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21
Q

give examples of molecules can pass through cell membranes in simple diffusion

A

oxygen and carbon dioxide

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22
Q

how do fat soluble molecules such as steroid hormones diffuse through cell membrane

A

even if they are larger, they diffuse through cell membranes as they dissolve in the lipid bilayer. they still move down their concentration gradient.

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23
Q

is water soluble or insoluble in lipids

A

insoluble because they are polar

24
Q

what is the name of the specific water channel protein

A

aquaporins

25
Q

what is the role of aquaporins

A

in membranes where a very high rate of water movements are required aquaporins allow water molecules to cross the membrane

26
Q

which molecules diffuse freely down the concentration gradient

A

non polar molecules

27
Q

what does the hydrophobic interior of the membrane do

A

repels substance with a positive or negative charge so they can’t easily pass through.

28
Q

how fast do polar molecules diffuse through

A

polar molecules with a slightly negative or slightly positive charge diffuse through at a slow rate

29
Q

which size molecules diffuse through faster

A

smaller molecules diffuse faster than larger molecules

30
Q

how is the concentration gradient maintained

A

molecules entering cells pass into organelles and then used for metabolic reactions. this maintains the concentration gradient and keeps more of the molecules entering the cell.

31
Q

give examples of how the concentration gradient is maintained

A

oxygen diffusing into the cytoplasm of respiring cells then diffuse into mitochondria and used for aerobic respiration
carbon dioxide diffusing into the palisade mesophyll cells of a plant leaf will then diffuse into chloroplasts and used for photosynthesis

32
Q

how is the rate of simple diffusion affecting

A

simple diffusion relies on the molecules own kinetic energy. so factors altering the kinetic energy will affect the rate of diffusion

33
Q

how does temperature affect the rate of diffusion

A

if temperature increases, molecules have more kinetic energy so rate of diffusion increases. as they lose heat, diffusion slows down

34
Q

how does the distance of diffusion affect the rate of diffusion

A

the thicker the membrane across which molecules diffuse, the slower the rate of diffusion

35
Q

how does surface area affect the rate of diffusion

A

more diffusion takes place across a larger surface area. cells specialised for absorption have extensions have microvilli which increase surface area

36
Q

how does the size of the diffusing molecules affect the rate of diffusion

A

smaller ions or molecules diffuse more rapidly than large molecules

37
Q

how does the concentration gradient affect the rate of diffusion

A

the steeper the gradient, the faster the diffusion down the gradient.

38
Q

what is the phospholipid bilayer a barrier to

A

polar molecules and ions

39
Q

what do membranes contain that allow polar substances to pass through

A

channel proteins

40
Q

what is facilitated diffusion

A

diffusion across a membrane which uses channel proteins

41
Q

how do small ions diffuse through facillitated diffusion

A

through channel proteins embedded within the cell membrane. some of these open or close in response to a specific messenger or a change in voltage across the membrane

42
Q

what is special about membranes with protein channels

A

they are selectively permeable as most protein channels are specific to one molecule or ion.

43
Q

what else can facilitated diffusion involve

A

carrier proteins

44
Q

what is special about carrier proteins

A

they can change shape when a specific molecule binds

45
Q

what is similar about simple and facilitated diffusion

A

they both occur down the concentration gradient

46
Q

what does the rate of facilitated diffusion depend on

A

temperature, concentration gradient, membrane surface area and thickness but also affected by the number of channel proteins present

47
Q

how does the number of channel proteins affect facilitated diffusion

A

the more protein channels, the higher the rate of diffusion

48
Q

what do cholesterol molecules within the membrane do

A

they reduce the permeability of the membranes to small water-soluble molecules.

49
Q

how do glucose molecules pass through the membrane

A

glucose molecules are too large to diffuse through the water filled protein channel in a membrane but they can bind to a transmembrane carrier protein which then opens to allow the glucose to pass out on the other side of the membrane

50
Q

how are cells able to control the types of molecules that pass in or out

A

different cell types have membranes with differing proportions of transmembrane protein channels and carrier proteins.

51
Q

describe the mechanism of diffusion for lipid soluble molecules

A
  • lipid soluble molecules diffuse through the plasma membrane from a region of high concentration outside the cell to a region of low concentration in the cytoplasm until they reach equilibrium
52
Q

describe the mechanism of diffusion for lipid insoluble solutes

A
  • lipid insoluble solutes (such as sugars or amino acids) can’t diffuse freely through the lipid bilayer due to their size or polarity. the carrier molecule binds with a molecule, such as glucose on the outside of the cell membrane. the carrier molecules changes shape and releases the molecule on the inside of the cell membrane
53
Q

describe the mechanism for diffusion for small lipid insoluble molecules

A

they travel through channel proteins. these open or close in response to a specific messenger. these are gated channel proteins

54
Q

describe the mechanism of diffusion for the transport of water

A

through aquaporins which are channel proteins. they travel by diffusion or osmosis.

55
Q

how does diffusion occur in neurones

A

neurone plasma membranes have many channels specific to either sodium or potassium ions. the diffusion of these ions into and out of the neurone axon is crucial for the conduction of nerve impulses. at synapses, there are also calcium ion channels and chloride ion channels.

56
Q

how does diffusion occur in epithelial cells

A

the plasma membranes of epithelial cells that line your airways have chloride ion channels and these play a crucial role in regulating the composition of mucus to trap pathogens and particles.

57
Q

how is the rate of diffusion calculated

A

using Ficks law
surface area x difference in concentration/length of diffusion path (membrane thickness)