The Developmental Origins of the Gut and Accessory Organs Flashcards
What is the gut?
A tube with accessory tubes that aid in digestion.
What are the accessory organs of the gut?
The salivary glands, liver, gall bladder and pancreas.
What organs arise from the gut but are not involved in nutrient extraction?
The lung and thyroid
What do the mouth parts arise from?
The branchial arches
What structures other than mouth parts do the branchial arches form?
Structures in the ear, head and neck.
What is the developmental stage of the human embryo at 32 days?
The four branchial arches are arranged symmetrically with the laryngeal pouch between.
What does the laryngeal pouch develop into?
The laryngeal groove
What does each segment of the branchial arches contain?
Cells that will develop into nerves, connective tissue and arteries surrounded by mesodermal tissue.
What kind of tissue is found on the outside of each branchial arch?
Ectodermal tissue
What kind of tissue is found on the inside of each branchial arch?
Endodermal tissue
What is the valley between the outside of each branchial arch called?
A cleft
What is the valley between the inside of each branchial arch called?
A pouch
What do the pouches give rise to?
The auditory tube, thymus and thyroid.
What do the clefts give rise to?
The skin of the ear, neck and eardrum.
What does the gut develop as?
An endodermal tube
What surrounds the endoderm of the gut and forms muscle and connective tissue?
The splanchnic mesoderm.
What provides nutrients to the embryo before the development of the placenta?
The yolk sac.
When does the foregut start to move and develop?
In week 4
What developmental activities are occurring in week 6?
The formation of the trachea. The stomach is fully developed and the dorsal and ventral pancreas are developing.
When does the hepatic bud that will become the liver form?
Week 4
What happens in week 5?
The hepatic bud develops more and starts to differentiate cells into hepatic cells.
What happens in week 6?
- The buds of the endoderm form the pancreas
- The secretion of enzymes and endocrine secretion hormones begins
- The pancreas is attached the the gut by the pancreatic duct
- The pancreatic buds converge to form one organ with acini and Islets of Langerhans
What does the dorsal pancreatic bud form?
The exocrine pancreas
How does the dorsal pancreas change in week 6?
It elongates and grows around the ventral pancreatic duct.
What are the 5 main regions of the gut?
- The mouth and salivary glands
- The pharynx and oesophagus
- The stomach
- The small intestine (duodenum, ileum and jejunum)
- The large intestine (colon, rectum and anus)
What initiates the process of digestion?
Chewing
Where does most digestion occur?
In the lumen of the small intestine.
What is the function of the large intestine?
Removes water and electrolytes