The CNS Flashcards

1
Q

What does the CNS consist of

A

Brain and spinal chord

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2
Q

What is the difference between grey and white matter

A

Grey matter contains cell bodies of neurones and a lot of glial cells
White matter contains myelinated neuronal axons

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3
Q

Describe the cerebrum/cerebral cortex

A

Grey matter outside, white inside

70% of grey matter hidden in sulci

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4
Q

Compare the primary and association cortex

A

Primary cortex - has a distinct function

Association cortex – more complex function, ‘higher processing’

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5
Q

What are the 4 lobes and what are they involved in

A

frontal - primary motor cortex + motor association area responsible for voluntary movement
temporal - Primary somatosensory cortex responsible for interpretation of sensory info
parietal - Primary auditory cortex and auditory association cortex responsible for hearing
occipital - Primary visual cortex and visual association area responsible for vision

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6
Q

What is the corpus callosum

A

white matter tract

interconnects corresponding parts of 2 hemispheres

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7
Q

What is the function of the basal ganglia

A

Controls posture and movement

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8
Q

What are the cerebral hemispheres made up of

A

cortex and basal ganglia

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9
Q

What is the function of the cerebellum

A

Coordinating movement

Learning fine motor skills

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10
Q

Describe the structure of the cerebellum

A

Attached to the brainstem posteriorly via 3 penduncles
Grey cortex and white matter
connected to the vestibular system for balance
Spinal cord and muscles
Motor cortex and thalamus

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11
Q

What is the diencephalon made up of

A

Hypothalamus and thalamus

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12
Q

What is the function of the diencephalon

A

hypothalamus: homeostasis - temp. hunger, thirst, hormone
thalamus: integration of somatic and special senses
relays info between the cerebral cortex and lower structures
Emotional status and consciousness

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13
Q

What are the functions of the brain stem

A

Controls vital functions (breathing, HR, BP)

Controls consciousness and sleep-wake cycles

Responsible for protective reflexes (cough, sneeze, gag)

Site of origin of cranial nerves innervating head and neck

Ascending and descending tracts connect forebrain and spinal cord

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14
Q

What is the corpus striatum made up of

A

caudate and putamen

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15
Q

What structures form the lentiform nucleus

A

Putamen and globus palladus

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16
Q

What is the brain stem made up of

A

midbrain
pons
medulla oblongata

17
Q

Describe the structure of the spinal cord

A

Grey matter on the inside
White matter on the outside
Contained within the vertebral column
Surrounded by meninges

18
Q

What is contained in the grey matter

A

dorsal horns - interneurones for sensory function

ventral horns - motor neurone cell bodies for motor function

19
Q

What are the connections in the cerebrum

A

Short connections between adjacent segments
Long tracts that connect all levels of the spinal cord
Commissural fibres go between hemispheres

20
Q

What are the functions of the spinal cord

A

Supplies motor, sensory and autonomic innervation to body through spinal nerves

Mediates reflexes

Contains ascending and descending tracts to communicate with the brain

21
Q

What are the three layers of the meninges from the outermost layer and describe them

A

Dura mater - tough and protective, adherent to bone, space between forms sinuses
Arachnoid mater - thin membrane attached to the dura
Pia mater - delicate membrane closely adherent to the brain and spinal cord

22
Q

Which layer of the meninges contains CSF

A

Subarachnoid space between arachnoid mater and Pia mater contains the CSF

23
Q

Describe epidural haemorrhage

A

arterial bleeding
headache, drowsiness, vomiting, seizure
promptly after injury
between dura mater and skull

24
Q

Describe subdural haemorrhage

A

venous bleeding
headache, drowsiness, vomiting, seizure
symptoms delayed by days or weeks
between Pia mater and dura mater

25
Describe the basic structure of the cranial fossae
anterior cranial fossa: frontal lobe middle cranial fossa: temporal lobe posterior cranial fossa: cerebellum + brainstem
26
What volume of CSF is produced each day and where
500ml from the choroid plexus in the ventricles
27
How much CSF flows at one time
150ml
28
Compare CSF to blood
Fewer cells Less protein Low potassium and calcium High magnesium and chloride
29
What are the functions of CSF
Shock absorbing – protection from trauma Removes waste products from cellular metabolism Supplies neurones with nutrients (secondary to blood) Contains immune cells
30
Describe the flow of blood for the lateral ventricle onwards
1. Lateral ventricles (cerebral hemispheres) 2. 3rd ventricles (Diencephelon) 3. Cerebral aqueduct (Midbrain) 4. 4th ventricle (Pons and medulla) 5. Subarachnoid space 6. Venous sinus via the arachnoid villi/granulations
31
What is hydrocephalus
An increase in CSF volume
32
How can communicating hydrocephalus be caused by a block in CSF absorption
meningitis head injury congenital sub-arachnoid haemorrhage
33
What can a non communicating hydrocephalus be caused by
Block in ventricular system Aqueduct stenosis Ventricular tumour
34
What is the treatment of hydrocephalus
Shunt - thin tube that's surgically implanted in the brain and drains away the excess fluid. An endoscopic third ventriculostomy (ETV) can sometimes be used as an alternative to shunt surgery.
35
What is the limbic system
Made up from different parts of the brain Mostly to do with memory Consists of the thalamus, hypothalamus, amygdala, hippocampus, basal ganglia, cingulate gyrus