The circulatory system Flashcards
Continuous capillaries
intercellular clefts
Skin, muscle, lungs, CNS
Allows fluid and small solutes to enter/exit intercellular clefts
Fenestrated capillaries
Pores - fenestrations
Kidney, small intestine, endocrine glands
Filtration, absorption or secretion
Sinusoidal capillaries
Large fenestrations and spaces between - sinusoids
Liver, lymphoid, bone marrow, adrenal medulla
Very leaky - allow large proteins to enter/exit
Blood pressure
Force exerted on a vessel wall by the blood in that vessel
Mean arterial pressure MAP
Pressure that propels blood through the vessels
Declines with increasing distance to heart
Equation = Diastolic pressure (⅓ pulse pressure)
Pulse pressure
Systolic pressure - diastolic pressure
Arterial blood pressure
How much elastic artery can be stretched - compliance
Regulation of blood pressure
- Autoregulation
- Neural regulation
- Renal regulation
- Endocrine regulation
Cardiac output to control BP
Rapid, short term regulation of BP and blood flow
determines blood pressure
Resistance to control BP
Peripheral resistance rapid, short term regulation of BP and blood flow
Change arterial diameter
Blood volume to control BP
Slower, long term regulation of BP
Controlled by renal and endocrine mechanisms
Autoregulation
Occurs within tissues
Altering arteriole diameter to regulate blood flow into capillary beds
Metabolic control - Co2 O2 and pH
Myogenic (muscle) control and reduced stretch