The Cell Cycle Flashcards

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1
Q

What are the phases of the cell cycle?

A
  • Interphase
    • G1
    • S
    • G2
  • M
    • Mitosis
    • Cytokinesis
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2
Q

What happens in G1

A
  • replicate mitochondria, robosomes, ER
  • increase cell size
  • Includes a restriction point
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3
Q

What happens in S

A

Clone DNA to create 2 chromatids joined at the centromere

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4
Q

What happens in G2

A
  • Checkpoint
    • enough organelles?
    • correctly replicated DNA?
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5
Q

What happens in M

A
  • Prophase
  • Metaphase
  • Anaphase
  • Telophase
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6
Q

Prophase

A
  • Chromatin condenses into chromosomes
  • centrioles go to poles
  • spindle fiber and aster formation
  • nuclear membrane dissolves
  • kinetochore fibers attach to kinetochores
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7
Q

Metaphase

A

microtubles align the chromosomes at the metaphase plate

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8
Q

Anaphase

A

sister chromatids are pulled apart by shortening of the kinetochore fibers

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9
Q

Telophase

A
  • spindle apparatus disappears
  • nuclear membranes form
  • chromosomes relax
  • cytoplasm and organelles are split in cytokinesis
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10
Q

What are the phases of meiosis

A
  • Prophase I and II
  • Metaphase I and II
  • Anaphase I and II
  • Telophase I and II
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11
Q

General discription of meiosis I

A

reductional division: homologous chromosomes are separated creating 2 haploid daughter cells

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12
Q

prophase I

A
  • chromatin condenses into chromosomes
  • spindle apparatus forms
  • nuclear membrane breaks down
  • synapsis
    -homologous chromosomes (maternal and parental) form a tetrad held together by the synaptonemal complex
    -crossing over can occur at chiasmata
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13
Q

Why is crossing over important

A
  • can unlink linked genes which increases genetic variability of gametes
  • explains Mendel’s 2nd law of independent assortment
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14
Q

metaphase I

A
  • tetrads align at the metaphase plate
  • each homologous pair attaches to its own kinetorchore fiber
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15
Q

anaphase I

A
  • disjuction: the maternal and paternal chromosomes separate
  • accounts for Mendel’s 1st law of segregation
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16
Q

telophase I

A
  • nuclear membranes form
  • cells now haploid
17
Q

interkinesis

A
  • may have a brief intermission between meiosis I and II
  • chromosomes may uncoil a little
18
Q

general description of meosis II

A

equational division: sister chromatids are separated which does not chance ploidy

19
Q

prophase II

A
  • nuclear membranes dissolve
  • centrioles go to the poles
  • spindle apparatus forms
20
Q

metaphase II

A

chromosomes align at the metaphase plate

21
Q

anaphase II

A

sister chromatids are pulled apart

22
Q

telophase II

A

nuclear membranes form

23
Q

differences between mitosis and meiosis

A
  • mitosis
    -2n to 2n
    -somatic cells
    -homologous chromosomes do not pair
    -no crossing over
  • meiosis
    -2n to n
    -sex cells only
    -homologous chromosomes pair
    -can have crossing over