The Bits

Question 1

Kinesin-13

Answer 1

Microtubule catastrophe fator

Question 2

XMAP215

Answer 2

Microtubule growth protein

Question 3

Stathmin

Answer 3

Promotes depolymerization by curving

Question 4

Katanin

Answer 4

Severs microtubules at a single point

Question 5

MAP2

Answer 5

Bundling protein that makes a “grid like formation of microtubules

Question 6

Tau

Answer 6

Bundling protein that makes small clusters of microtubules

Question 7

+TIP

Answer 7

Proteins at the end of the microtubule that help with a number of different functions

Question 8

Kinesin

Answer 8

Plus end motor protein

Question 9

Dynein

Answer 9

Minus end motor protein (low affinity)

Question 10

Profilin

Answer 10

Binds to actin and creates high affinity for the plus end of an actin filament

Question 11

Thymosin

Answer 11

Bonds to actin but blocks the binding site for the actin filament

Question 12

Arp2/3

Answer 12

Mimics the plus end of a n actin filament while connected laterally to an existing actin filament, creating branching

Question 13

Formin

Answer 13

Ring-like structure that sits on the barbed plus end of an actin filament and grabs g-actin

Question 14

End cap

Answer 14

Stabilizes the actin filament at either the plus end or minus end (can exist on both ends at the same time

Question 15

Cofilin

Answer 15

Severs actin filaments by twisting the alpha helices until breakage

Question 16

Fimbrin

Answer 16

Bundles actin closely together

Question 17

Alpha-actinin

Answer 17

Makes looser bundles of filaments

Question 18

Filamin