Summer Supplement Flashcards

Slide Set 1

1
Q

What makes cell biology reductionist?

A

Studying parts helps understand the whole

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2
Q

Discovery of cells stems from the inventions of..?

A

The microscope by Robert Hooke

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3
Q

Cell theory was articulated in ________ by _______.

A

mid-1800s (Schleiden, Schwann, and Virchow)

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4
Q

Cell theory

A

Living things are made of one or more cells, cells are the smallest unit of life, cells arise from pre-existing cells.

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5
Q

What are cultured cells?

A

Cells that are grown and reproduce for extended periods (cultured cells are important for cell biology)

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6
Q

Example of cultured cells

A

HeLa cells (isolated from a tumor from a cancer patient in 1951 and still cultured today)

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7
Q

Prokaryotes include…

A

Bacteria and archea that arose ~3.7 billion years ago

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8
Q

Eukaryotes include…

A

Protists, animals, plants, and fungi

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9
Q

Prokaryotes and Eukaryotes can be differentiated by…

A

Their size and different type of organelles

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10
Q

What is a chemoautotroph?

A

Organisms that use carbon dioxide as a carbon source and oxidize inorganic materials to extract energy

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11
Q

The first prokaryote appeared _____ years ago. The first unicellular Eukaryote appeared _____ years ago.

A

~3900 - 2500 million and 1850 million years ago (Prokaryotes gave rise to eukaryotes)

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12
Q

What are the major divisions of life?

A

Bacteria, archea, eukaryotes

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13
Q

What is endosymbiont theory?

A

Organelles in eukaryotic cells evolved from smaller prokaryotic cells upon unsuccessful consumption (mitochondria and chloroplasts)

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14
Q

Types of prokaryotic cells include…

A

Archea (methanogens, halophiles, acidophiles, and thermophiles) and Bacteria

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15
Q

What are the smallest known cells?

A

Mycoplasma

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16
Q

What are cyanobacteria?

A

Photosynthetic bacteria that give rise to green plants and an oxygen-rich atmosphere

17
Q

What is nitrogen fixation?

A

Chemical process that turns molecular nitrogen into ammonia or other nitrogen compounds (some bacteria are capable of doing this)

18
Q

What is Vorticella?

A

Complex ciliated protist with contractile ribbon in the stalk and a large macronucleus (example of how unicellular eukaryotes are complex)

19
Q

What is “differentiation” in terms of cell specialization?

A

A step in embryonic development where cells develop different arrangements and organelles in order to serve a specific function in the organism (despite differentiation, the cells will still have many common features)

20
Q

What are the most abundant atoms in organic molecules?

A

CHON (Carbon, Hydrogen, Oxygen, and Nitrogen) –> In order of most to least abundant

21
Q

What are the valences for each of the atoms in organic molecules?

A

C - 4, H - 1, O - 2, N - 3

22
Q

Subunits create macromolecules with what type of bonding?

A

Covalent bonding

23
Q

Macromolecules, in order to undergo macromolecular assembly, associate with what type of bonding?

A

Noncovalent bonding

24
Q

What are the types of noncovalent bonds?

A

Ionic bonding, Hydrogen bonding, and Van der Waals interactions

25
Q

What is an ionic bond?

A

Attraction between 2 ions (charged molecules) Weakened by water and significant between large, biological molecules. Negative meets positive.

26
Q

What is hydrogen bonding?

A

Hydrogen attracts an atom outside of it;s original bond (Usually an electronegative atom, as bonded hydrogens will still have a partial positive charge) Explains how water molecules arrange themselves

27
Q

What are Van der Waals forces?

A

Attraction between nonpolar molecules (Occurs due to transient dipole formation - Electrons move in electron clouds meaning charges are constantly moving) Molecules need to be very close togethe to experience this interaction

28
Q

What are hydrophobic interactions?

A

Molecules that are hydrophobic, i.e. uncharged molecules, don’t like to touch hydrogen bonds, and avoid doing so by “wrapping” themselves up in proteins or other hydrophobic molecules

29
Q

What is molecular complimentary?

A

Noncovalent interactions between 2 proteins, or a protein and DNA (Makes biological macromolecules)

30
Q

What are the 3 interaction determining properties of water?

A

Assymetric, Does not evaporate easily, Excellent solvent

31
Q

What does it mean for a molecule to be amphoteric?

A

The molecule can act as an acid or a base (i.e. water)

32
Q

What is a buffer and what does it do?

A

A buffer is a (usually) amphoteric compound, or mixture of 2 compunds (an acid and a base) that helps resist changes to the body’s pH

33
Q

What is an example of a buffer?

A

Bicarbonate (HCO3-) and Carbonic acid (H2CO3) –> Buffer for blood

34
Q

What are the 4 types of macromolecules? What are their monomers?

A

Carbohydrates (sugars), Proteins (amino acids), Lipids (fatty acids), Nucleic acids (nucleotides)