The Ageing Endocrine And Immune Systems

Question 0

What changes does hypothalamic ageing cause?

Answer 0

Decreased sleep 
Disturbed sleep/wake cycle 
Diminished appetite 
Poor thermoregulation 
Blunted stress response

Question 1

What does the hypothalamus control?

Answer 1

Thirst
Sleep
Appetite

Question 2

What changes occur in the pituitary structure in ageing?

Answer 2

Diffuse fibrosis
Decrease in deriving
Incidence of adenomas
Decrease in basophilics and acidophilics

Question 3

What changes occur in growth hormone with ageing?

Answer 3

Growth hormone releasing hormone decreases
Therefore growth hormone secretion falls
Fall in IGF-1
Fewer GH receptors
Reduction in protein synthesis, immune functions and lean body and bone mass

Question 4

What are the side effects of growth hormone injections?

Answer 4

Arthralgia
Oedema
Hyperglycaemia
Cancer risk

Question 5

Less T4 is concerted into T3

TRUE or FALSE

Answer 5

True

Question 6

How does parathyroid hormone increase calcium?

Answer 6

Stimulate release of calcium from bone
Osteoclasts
Calcium resorption in kidney
Vitamin D production

Question 7

What are the risks of HRT?

Answer 7

CVA risk
Coronary events
Breast cancer