Thalassemias: Chesney * Flashcards
1
Q
What are thalassemias?
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2
Q
What is the selective advantage of thalassemias?
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3
Q
Why is the alpha chain of hemaglobin very important?
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4
Q
What is the normal makeup of hemoglobin in the adult?
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5
Q
What is beta thalassemia?
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6
Q
What is the epidemiology of beta thalassemia?
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7
Q
Why does Beta thalassemia case anemia?
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8
Q
What happens to bones in beta thalassemia?
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9
Q
What happens to the liver and spleen in beta thalassemia?
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10
Q
What are the signs and symptoms of beta-thalassemia?
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11
Q
Why do patients with Thalassemia get iron overload?
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12
Q
Why is there hypercoagulability in thalassemia?
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13
Q
What can reduce the thrombotic complications of thalassemia?
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14
Q
Why is endocrine and bone disease associated with thalassemia?
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15
Q
Why is the clinical presentation of beta thalassemia so variable?
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