TG - 1 Flashcards by Tania Nolli

treatment for mild acne

benzoyle peroxide

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treatment for widespread acne

oral antibiotics: erythromycin/tetracycline or COCP

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treatment for severe acne

retinoids: tretinoin

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tretinioin side risks

teratogenic, photosensitivity

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flushing erythema on face

acne rosacea

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what is blepharitis

inflammation of the eyelid

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in what condition do you see blepharitis

acne rosacea

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what is rhinophyma

large nose seen in acne rosacea

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flushing triggered by alcohol/coffee/slicy food

acne rosacea

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mild acne rosacea treatment

topical metronidazole

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severe acne rosacea treatment

oral tetracycline / erythromycin

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BCC with central ulcer is called

rodent ulcer

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small BCC management

curettage and cautery, cryotherapy

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severe BCC treatment

Moh’s micrographic surgery (progressive excision)

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what is bowens disease

Cutaneous SCC in situ

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Bowen disease treatment

punch biopsy; cryotherapy + topical 5FU; Moh’s micrographic surgery

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Diagnosis: slowly expanding well-circumscribed erythematous patch

Bowens

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what area of skin is affected in cellulitis

dermis and below

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what pathogen causes cellulitis

strep (esp group A) or staph

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deep skin infection with poorly demarcated borders

cellulitis

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name for more superficial skin infection

erysipelas

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cellulitis treatment

fluclox

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erysipelas treatment

pen V

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fungal infection of skin is called

Dermatophytosis (tinea)

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tinea capitis is

scalp

tinea pedis is

feet

tinea manuum

hands

tinea corporis

trunk/body

what must be avoided in skin fungal infections

steroids

anti fungal drugs end in what

- azole (imidazole) | * * terbinafine**

tinea investigations

woods light/microscopy

eczema distribution

flexural distribution - elbows, knees, neck, cheeks (in children)

what is eczema herpeticum

complication of eczema. get fever

painful, blisters, punched-out erosions, fever

eczema herpeticum

eczema treatment

emollients

oval erythematous plaques on extremities

discoid eczema

which skin condition can be intently itchy at night

discoid eczema

hand eczema with with excessive sweating

pompholyx

discoid eczema treatment

moisturisers

pompholyx treatment

topical steroids

impetigo treatment

topical fusidic acid

lichen planes is associated with what other infection

hep C

lichen planes treatment

topical steroids

what is PUVA

psoralins + UVA

when might you use PUVA

lichen planus | pompholyx (discoid eczema)

ABCDE

asymmetry, border, colour, diameter, evolution; itching, bleeding

margin for melanoma excision biopsy

2mm

melanoma treatment

wide local excision

where does melanoma spread to

lymph nodes, liver, lung, bone, brain

bug that causes new fasc

Group A strep

symptoms of nec fasc

• Symptoms - disproportionately severe pain with initially minor skin changes, systemic upset

what might happen in nec fasc

septic shock

hoe does pemphigus and pemphigoid differ

pemphigus: superficial epidermis pemphigoid: sub epidermal

painful flaccid blisters

pemphigus

different types of pemphigus

vulgaris (commonest), foliaceus (anti-DSG1 antibodies), paraneoplastic

which has oral involvement: pemphigus or pemphigoid

pemphigus

bullous pemphigoid immunofluorescence will show what

IgG/C3 at dermal junction

how does treatment or pemphigoid and pemphigus vary

pemphigus: oral prednisolone (think oral = systemic = systemic treatment) pemphigoid: topical steroids

pemphigoid investigations

direct immunofluorescence: shows IgG/C3 at dermal junction

psoriasis is mediated by what immune cell

T cells

psoriasis is associated with what other conditions

IBD

HLA associated with psoriatic arthritis

HLA-B27/DR4

1st line psoriasis treatment

emollients + topical vit D

2nd line psoriasis treatment

phototherapy (UVB, PUVA), methotrexate

treatment for scalp/face psoriasis

scalp - topical salicylic acid, olive oil; facial - short-term topical steroids

potent topical steroid used for psoriatic flares

beclometasone 0.1%

scabies treatment

permethrin

SCARs

Severe cutaneous adverse reactions (drugs, viral, URTI)

6 drugs that cause skin eruption (SCARs)

trimethoprim, allopurinol, carbamazepine, sulfasalazine, aspirin, sertraline

target lesions

Erythema multiforme

symmetrical papular rash spreading inward from extremities

erythema multiforme

what is steven-johnson syndrome

Type III hypersensitivity usually to drugs

Brown ‘velvety’ rash over flexural areas esp. axillae

Acanthosis nigricans

Acanthosis nigricans is associated with which type of conditions

conditions of insulin resistance / impaired glucose tolerance • Associations - hypothyroidism, GI malignancy, DM, obesity, PCOS, acromegaly, Cushing’s

skin condition associated with coeliacs

dermatitis herpetiformis

dermatitis herpetiformis treatment

dapsone

dermatitis herpetiformis investigation

skin biopsy

erythema nodosum treatment

NSAIDs

pre-tibial yellowing (fat deposits)

Necrobiosis lipoidica

who gets Necrobiosis lipoidica

those with diabetes and IBD

who gets Pyoderma gangrenosum

those with UC and RA

investigation for pyoderma gangrenosum

p-ANCA

Pyoderma gangrenous treatment

prednisolone

what skin condition do people with parkinson get

seborrhoea dermatitis

seborrhoea dermatitis treatment

ketaconazole

what cause scalded skin syndrome

• Strains of Staph. aureus release epidermolytic toxins degrading desmoglein-1

scalded skin syndrome treatment

fluclox

indurated nodular crusted tumour presenting as non-healing ulcer

SCC

SCC treatment

complete surgical excision

what is urticaria

subdermal angio-oedema

sarcoid pneumonic

Causes of erythema nodosum ``` NO NO cause (idiopathic – 60% of cases) D Drugs (sulfonamides, penicillin) O Oral contraceptive pill S Sarcoidosis U Ulcerative colitis M Microbiology (eg streptococcal throat infection, tuberculosis) ```