TG - 1 Flashcards

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1
Q

treatment for mild acne

A

benzoyle peroxide

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2
Q

treatment for widespread acne

A

oral antibiotics: erythromycin/tetracycline or COCP

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3
Q

treatment for severe acne

A

retinoids: tretinoin

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4
Q

tretinioin side risks

A

teratogenic, photosensitivity

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5
Q

flushing erythema on face

A

acne rosacea

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6
Q

what is blepharitis

A

inflammation of the eyelid

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7
Q

in what condition do you see blepharitis

A

acne rosacea

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8
Q

what is rhinophyma

A

large nose seen in acne rosacea

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9
Q

flushing triggered by alcohol/coffee/slicy food

A

acne rosacea

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10
Q

mild acne rosacea treatment

A

topical metronidazole

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11
Q

severe acne rosacea treatment

A

oral tetracycline / erythromycin

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12
Q

BCC with central ulcer is called

A

rodent ulcer

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13
Q

small BCC management

A

curettage and cautery, cryotherapy

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14
Q

severe BCC treatment

A

Moh’s micrographic surgery (progressive excision)

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15
Q

what is bowens disease

A

Cutaneous SCC in situ

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16
Q

Bowen disease treatment

A

punch biopsy; cryotherapy + topical 5FU; Moh’s micrographic surgery

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17
Q

Diagnosis: slowly expanding well-circumscribed erythematous patch

A

Bowens

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18
Q

what area of skin is affected in cellulitis

A

dermis and below

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19
Q

what pathogen causes cellulitis

A

strep (esp group A) or staph

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20
Q

deep skin infection with poorly demarcated borders

A

cellulitis

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21
Q

name for more superficial skin infection

A

erysipelas

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22
Q

cellulitis treatment

A

fluclox

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23
Q

erysipelas treatment

A

pen V

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24
Q

fungal infection of skin is called

A

Dermatophytosis (tinea)

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25
Q

tinea capitis is

A

scalp

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26
Q

tinea pedis is

A

feet

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27
Q

tinea manuum

A

hands

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28
Q

tinea corporis

A

trunk/body

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29
Q

what must be avoided in skin fungal infections

A

steroids

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30
Q

anti fungal drugs end in what

A
  • azole (imidazole)

* * terbinafine**

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31
Q

tinea investigations

A

woods light/microscopy

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32
Q

eczema distribution

A

flexural distribution - elbows, knees, neck, cheeks (in children)

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33
Q

what is eczema herpeticum

A

complication of eczema. get fever

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34
Q

painful, blisters, punched-out erosions, fever

A

eczema herpeticum

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35
Q

eczema treatment

A

emollients

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36
Q

oval erythematous plaques on extremities

A

discoid eczema

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37
Q

which skin condition can be intently itchy at night

A

discoid eczema

38
Q

hand eczema with with excessive sweating

A

pompholyx

39
Q

discoid eczema treatment

A

moisturisers

40
Q

pompholyx treatment

A

topical steroids

41
Q

impetigo treatment

A

topical fusidic acid

42
Q

lichen planes is associated with what other infection

A

hep C

43
Q

lichen planes treatment

A

topical steroids

44
Q

what is PUVA

A

psoralins + UVA

45
Q

when might you use PUVA

A

lichen planus

pompholyx (discoid eczema)

46
Q

ABCDE

A

asymmetry, border, colour, diameter, evolution; itching, bleeding

47
Q

margin for melanoma excision biopsy

A

2mm

48
Q

melanoma treatment

A

wide local excision

49
Q

where does melanoma spread to

A

lymph nodes, liver, lung, bone, brain

50
Q

bug that causes new fasc

A

Group A strep

51
Q

symptoms of nec fasc

A

• Symptoms - disproportionately severe pain with initially minor skin changes, systemic upset

52
Q

what might happen in nec fasc

A

septic shock

53
Q

hoe does pemphigus and pemphigoid differ

A

pemphigus: superficial epidermis
pemphigoid: sub epidermal

54
Q

painful flaccid blisters

A

pemphigus

55
Q

different types of pemphigus

A

vulgaris (commonest), foliaceus (anti-DSG1 antibodies), paraneoplastic

56
Q

which has oral involvement: pemphigus or pemphigoid

A

pemphigus

57
Q

bullous pemphigoid immunofluorescence will show what

A

IgG/C3 at dermal junction

58
Q

how does treatment or pemphigoid and pemphigus vary

A

pemphigus: oral prednisolone (think oral = systemic = systemic treatment)
pemphigoid: topical steroids

59
Q

pemphigoid investigations

A

direct immunofluorescence: shows IgG/C3 at dermal junction

60
Q

psoriasis is mediated by what immune cell

A

T cells

61
Q

psoriasis is associated with what other conditions

A

IBD

62
Q

HLA associated with psoriatic arthritis

A

HLA-B27/DR4

63
Q

1st line psoriasis treatment

A

emollients + topical vit D

64
Q

2nd line psoriasis treatment

A

phototherapy (UVB, PUVA), methotrexate

65
Q

treatment for scalp/face psoriasis

A

scalp - topical salicylic acid, olive oil; facial - short-term topical steroids

66
Q

potent topical steroid used for psoriatic flares

A

beclometasone 0.1%

67
Q

scabies treatment

A

permethrin

68
Q

SCARs

A

Severe cutaneous adverse reactions (drugs, viral, URTI)

69
Q

6 drugs that cause skin eruption (SCARs)

A

trimethoprim, allopurinol, carbamazepine, sulfasalazine, aspirin, sertraline

70
Q

target lesions

A

Erythema multiforme

71
Q

symmetrical papular rash spreading inward from extremities

A

erythema multiforme

72
Q

what is steven-johnson syndrome

A

Type III hypersensitivity usually to drugs

73
Q

Brown ‘velvety’ rash over flexural areas esp. axillae

A

Acanthosis nigricans

74
Q

Acanthosis nigricans is associated with which type of conditions

A

conditions of insulin resistance / impaired glucose tolerance
• Associations - hypothyroidism, GI malignancy, DM, obesity, PCOS, acromegaly, Cushing’s

75
Q

skin condition associated with coeliacs

A

dermatitis herpetiformis

76
Q

dermatitis herpetiformis treatment

A

dapsone

77
Q

dermatitis herpetiformis investigation

A

skin biopsy

78
Q

erythema nodosum treatment

A

NSAIDs

79
Q

pre-tibial yellowing (fat deposits)

A

Necrobiosis lipoidica

80
Q

who gets Necrobiosis lipoidica

A

those with diabetes and IBD

81
Q

who gets Pyoderma gangrenosum

A

those with UC and RA

82
Q

investigation for pyoderma gangrenosum

A

p-ANCA

83
Q

Pyoderma gangrenous treatment

A

prednisolone

84
Q

what skin condition do people with parkinson get

A

seborrhoea dermatitis

85
Q

seborrhoea dermatitis treatment

A

ketaconazole

86
Q

what cause scalded skin syndrome

A

• Strains of Staph. aureus release epidermolytic toxins degrading desmoglein-1

87
Q

scalded skin syndrome treatment

A

fluclox

88
Q

indurated nodular crusted tumour presenting as non-healing ulcer

A

SCC

89
Q

SCC treatment

A

complete surgical excision

90
Q

what is urticaria

A

subdermal angio-oedema

91
Q

sarcoid pneumonic

A

Causes of erythema nodosum

NO	NO cause (idiopathic – 60% of cases)
D	Drugs (sulfonamides, penicillin)
O	Oral contraceptive pill
S	Sarcoidosis
U	Ulcerative colitis
M	Microbiology (eg streptococcal throat infection, tuberculosis)