Testing New Therapeutics Flashcards
1
Q
what are the first three methods of testing drug-receptor interactions?
A
high-throughtput screeening, followed by cell based assay, followed by animal based models
2
Q
what are the 4 phases of drug clinical development?
A
safety verification
small scale patient trials
multicentre randomised double blind trials
post-marketing surveillance
3
Q
what is a congenital malformation?
A
anatomical abnormalities present at birth
4
Q
what is teratology?
A
study of abnormal development and the causes of congentical malformations
5
Q
what is a teratogen?
A
an agent that induces congenital malformations
