Testicular Tumors Flashcards
Seminoma
histology
large cells w/ clear cytoplasm, central nuclei
“fried egg” apperance
Seminoma
gross appearance
non-hemorrhagic
homogenous mass
Embryonal carcinoma
gross appearance
hemorrhagic mass with necrosis
Embryonal carcinoma
Tx
risks
Tx: chemo
risk: differeniation into mature tissue tumor, may produce glands
Embryonal carcinoma
tumor marker
hCG
Yolk sac/endodermal sinus tumor
population
histology
tumor marker
young children
Schiller-Duval bodies–glomeruloid-like histology
AFP elevation
*alpha-fetoprotein
Choriocarcinoma
potential
tumor marker
tissue resembles
very high malignancy potential
hCG is tumor marker
tissu resembles placenta, trophoblasts
*that all makes sense, b/c placental tissue wants to find blood vessels bad so there is early hematogenous spread
Teratomas in males
almost always malignant
Most germ cell tumors in men are
mixed tumor types
Leydig cell tumors
type
pathology
histology
sex cord stromal tumors–usually benign
produce androgen
Reinke crystals on histo
Reinke crystals
Leydig cell tumor
Most common testicular tumor in older men
lymphoma
