Prostate Flashcards
Chronic prostatitis presentation
pelvic or low back pain
Tender and boggy prostate
acute prostatitis
Cultures in chronic prostatitis
usually negative (!)
BPH related to which hormones
DHT
BPH occurs where in prostate
periurethral zone
makes perfect sense w/ Sx
Possible very bad, not so good complication of BPH
hydronephrosis
when ureter openings are compromised
Tx of BPH
alpha1 antagonists: terazosin
5alpha reductase inhibitors: finasteride
BPH is sensitive to what hormone
DHT
testosterone —> DHT
via 5-alpha reductase
The only way to definitively diagnose prostate adenocarcinoma
Bx
Gleason grading system
how does it work
out of 10, scored 1-5 of two separate Bx sites
based on architecture alone
nuclear atypia does not play a role
Prostate ca mets
blastic, often to lumbar spine or hip
alkaline phosphatase is often high