testicular cancer Flashcards
majority of testicular cancers are?
germ cell
germ cell tumours can be divided into ?
seminoma and non seminoma
which tumour develops in older men (>30)
seminoma (potato)
large, solid, homogenous mass?
seminoma (potato)
types of non seminoma?
yolk sac, choriocarcinoma, teratoma
main risk factor for testicular cancer?
undesceneded testes (cryptorchidism)
what is the tumour marker that is never raised in pure seminoma?
AFP never raised
tumour marker raised in seminoma?
PLAP
used to assess tumour burden
LDH
HCG is raised in ?
non summon that contains a TROPHOBLASTIC COMPONENT (Teratoma)
TT
lymph node spread of testicular tumours?
para aortic nodes
metastatic spread of testicular cancer?
lungs and brain
aged 30-65 with testicular cancer?
seminoma
what question would you ask for systemic enquiry for testicular cancer?
SOB (for lung mets)
1st line investigation for cancer?
Ultrasound then tumour markers then staging CXR CTCAP MRI pelvis
management of testicular cancer?
• Orchidectomy +/- radiotherapy or chemotherapy +/- retro peritoneal lymph node dissection.
during surgery for test cancer, what has to be done to the spermatic cord?
it has to be occluded to reduce the risk of spread
which tumour is radiosensitive?
seminoma
which is chemosensitive?
non seminoma
if absent cremasteric reflex?
torsion