Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

EMPIRE In-Service Review > Testicular Cancer > Flashcards

Testicular Cancer Flashcards

1
Q

Most common presentation of testes ca.

A

localized seminoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Most common age range at presentation

A

20-35 y.o.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Risk factors for testes cancer

A

Cryptorchidism
Family or personal hx of testes cancer
Intra-tubular germ cell neoplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Must perform orchiopexy before ____ to decrease testicular cancer rates

A

puberty

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Seminomas often have ____ that produce bHCG

A

synctiotrophoblasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Choriocarcinoma

VERY HIGH ____

Spreads via ____

Hemorrhagic ____ mets

A

v high bHCG

Hematogenous spread

hemorrhagic brain mets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

____ tumors are chemo/rads resistant

A

Teratoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

____ tumors are most commonly in pre-pubertal children

A

Yolk Sac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Imaging study for testicular mass

A

scrotal u/s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Tumor markers should be followed up ____ s/p orchiectomy

A

4-5 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Staging imaging

A

CT abd/pelvis

CXR (low risk) vs CT chest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Tumor confined to testes + epididymis w/o LVI

p___

A

pT1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Tumor confined to testes + epididymis w LVI OR tunica vaginalis invasion

p___

A

pT2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Tumor invading spermatic cord

p___

A

pT3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Tumor invading scrotum

p___

A

pT4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Nodal disease
only applies to RP nodes

N1 - ___ cm

A

N1 - <2cm
N2 - 2-5 cm
N3 - >5 cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Seminoma with <3cm Tumor confined to testes + epididymis w/o LVI

p___

A

T1a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Seminoma with >3cm Tumor confined to testes + epididymis w/o LVI

p___

A

T1b

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Seminoma confined to testes is always clinical stage ____

A

T1

T1a - pT1
T1b - pT2-4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Seminoma with RP nodal mets & S0-1 is clinical stage ___

A

T2

T2a - cN1
T2b - cN2
T2c - cN3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Seminoma with distant mets is clinical stage ___

A

T3

T3a - S1
T3b - S2
T3c - S3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Half life of AFP

A

5-7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

AFP is NEVER elevated in ____

A

seminoma

24
Q

Half life of bHCG

A

24-36h

25
Q

Half life of LDH

A

24 hrs

26
Q

Yolk sac has elevated ___ tumor marker

A

AFP

27
Q

Seminoma - localized or with pulmonary mets

____ risk disease

A

Good

28
Q

Seminoma with non-pulmonary mets

____ risk disease

A

Intermediate

29
Q

Non-seminoma with S1 tumor markers

____ risk disease

A

Good

30
Q

Non-seminoma with S2 tumor markers

____ risk disease

A

Intermediate

31
Q

Non-seminoma with S3 tumor markers OR mediastinal primary OR non-pulmonary mets

____ risk disease

A

Poor

32
Q

Right testes tumors spread to ____ LNs

A

inter-aortocaval

33
Q

Left testes tumors spread to ____ LNs

A

Para-aortic

34
Q

ITCGN ___% develop testes cancer

A

50

35
Q

ITCGN Treatment

A

Surveillance
Orchiectomy (100% cure)
XRT (100% cure)
Chemo (66% cure)

36
Q

Relapse rates for seminoma

Surveillance only - ___%
1 round of Carboplatin - ___%

A

Surveil - 14%

Chemo - 4%

37
Q

Median time to relapse for seminoma s/p orchiectomy

A

1.5 years

38
Q

Strongest risk factors for non-seminoma relapse

A

LVI

Embryonal tumors

39
Q

Relapse rates for seminoma (without risk factors)

Surveillance only - ___%
BEP x1 - ___%

A

15%

1%

40
Q

Relapse rates for seminoma (with risk factors)

Surveillance only - ___%
BEP x1 - ___%

A

40%

3%

41
Q

Treatment if node + at time of primary RPLND

N1 - ____
N2 - ____
N3 - ____

A

N1 - surveillance

N2 - EPx2 or BEPx2

N3 - BEPx3 or EPx4

42
Q

To preserve antegrade ejaculation after RPLND, spare ___ nerves

A

L1-L3 post-ganglionic sympathetic nerves

behind the IVC

43
Q

Bleomycin adverse effects

A

pulmonary toxicity

44
Q

Which stages of non-seminoma do you offer primary RPLND?

A

Stage IIA/B

  • do not perform with elevated tumor markers*
  • potential reduces chemo burden*
45
Q

Which stages of seminoma can you offer RT?

A

Stage IIA/B - nodal positive disease, 2-5 cm

46
Q

Must wait at least ____ s/p chemo to perform PET CT

A

6 weeks

47
Q

Seminoma s/p chemo

Next step if no mass or <3cm mass - ____

A

Surveillance

48
Q

Seminoma s/p chemo

Next step if >3cm mass - ____

A

PET CT

  • Negative - surveillance
  • Positive - resection
49
Q

Seminoma s/p chemo

Next step if tumor growth or tumor marker elevation - ____

A

2nd line chemo

TIP/VeIP

50
Q

Non-seminoma s/p chemo

Next step if no mass or <1cm mass with normal tumor markers - ____

A

Surveillance or RPLND

51
Q

Non-seminoma s/p chemo

Next step if >1cm mass with normal tumor markers - ____

A

post-chemo RPLND

52
Q

Non-seminoma s/p chemo

Next step if persistent elevated tumor markers - ____

A

2nd line chemo

TIP/VeIP

53
Q

Long term risks of chemo for testes ca patients

A

Cardiovascular disease

2ndary cancers

54
Q

Management of post-chemo distant mets

A

resect if possible

55
Q

Offer all patient ____ prior to treatment to maintain fertility

A

sperm banking

56
Q

Treatment after trans-scrotal orchiectomy

A

Observe vs excise scar vs RT

EMPIRE In-Service Review (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions