Test3 Neuropharmacology Flashcards
the study of drugs that alter processes controlled by the nervous system
neuropharmacology
the process of an action potential (electrical impulse) being delivered toward the axon
synaptic transmission
drugs are almost always
reversible
from precursor molecules-potential target from drug therapy
transmitter synthesis
in vesicles
transmitter storage
stimulated by electrical impulse
transmitter release
the body’s own natural process is a reversible binding process
receptor binding
- recycled
- degraded by enzymes (killed)
- diffused and float away
termination of transmission
after is disassociates with its receptor
termination of transmission
ultimately the impact of a drug on a neuronally regulated process is dependent on the ability of that drug to directly or indirectly influence receptor activity on target cells
drug effects
electrical impulse
axonal conduction
drugs can increase or decrease or cause production of other neurotransmitters
transmitter synthesis
agonist/antagonist
receptor binding
- blockade of reuptake
2. inhibit transmitter degradation
termination of transmitter action
neurotransmitter for synaptic NS (sweat glands) and neurotransmitter for parasympathetic NS
acetylcholine
sympathetic neurotransmitter except for sweat glands
norepinephrine
adrenaline-in kidneys
epinephrine
CNS neurotransmitter, dilates the vasculature of the kidneys
dopamine
dramatically enhance selectively
receptors
nerve-parasympathetic and sympathetic NS
nicotinic n
muscles-somatic motor system
nicotinic m
sweat glands-most organ
muscarinic
eyes dilate, constriction of arteries and veins and prostate, contraction of sphincter, no urine
alpha 1
whoa receptor-shuts down additional release of neurotransmitter in the synapse
alpha 2
