Test For Detoxification Function

Question 1

Assess the extent of liver damage

Answer 1

Enzyme test

Question 2

Indicator of cell injury in early or localized liver disease

Answer 2

Enzyme test

Question 3

Hepatic enzymes

Answer 3

ALT
AST
5N
GGT
LDH
OCT

Question 4

Diagnostic marker of hepatic failure

Answer 4

Ammonia

Question 5

Detoxified into urea (liver), then eliminated by the kidneys (urine)

Answer 5

Ammonia test

Question 6

Ammonia is neurotoxic that lead to coma?

Answer 6

Yes

Question 7

Ammonia test reference value

Answer 7

19-60 ug/dl

Question 8

Protein —-> amino acid

Answer 8

Proteolysis

Question 9

Amino acids ——> ammonia

Answer 9

Transamination and oxidation deamination

Question 10

Ammonia ——-> urea

Answer 10

Enzymatic synthesis in the urea cycle (krebs cycle)

Question 11

Specimen

Answer 11

Venous blood
- heparin, EDTA, potassium oxalate

Question 12

Specimen precautions

Answer 12

Smoking
Exercise
Probing of vein
Under filling of tube
Hemolysis

SEPUH

Question 13

Storage

Answer 13

Frozen

Question 14

Decrease in absorbance at 340 nm as NADPH is consumed

Answer 14

Glutamate dehydrogenase methods