Test 4 psych Flashcards
Rivastigmine(Exelon)
- Treatment to mild to moderate AD and PD
- Can be used in later stages
- Inhibits AChE selectively in the cortex and the hippocampus more than in other parts of the brain.
- This drug is advantageous for patients who do not respond to other anticholinergic drugs or who are in the later stages of AD
- Side effects: nausea, vomiting, and dizziness
- Transdermal form is effective and has fewer peripheral side effects as compared with the oral form.
tacrine(Cognex)
potential for hepatic toxicity, rarely used because of side effects
donepezil(Aricept)
– it requires only once-per-day dosing.
– Enhances cholinergic function by the reversible inhibition of the hydrolysis of Ach by AChE.
– Slows progression
– Effective when cholinergic neurons are intact.
– May produce gastrointestinal side effects by inhibiting AChE in the periphery
Glantamine (Razadyne)
- Treats mild to moderate AD
- It is a reversible inhibitor for AChE
- It increases the availability of ACh; affects nicotinic cholinergic receptors in such a way that AChE inhibition can theoretically be enhanced
- Shown to decrease agitation and to increase cognition
- Twice daily dosing
Memantine (Namanda)
- Treats moderate to severe AD
- It is an N-methyl-D-aspartate receptor antagonist that blocks the effects of excess glutamate.
- Blocks the excitotoxic effects of glutamate while allowing normal glutamate neurotransmission to occur.
Kubler Ross (5 Stages)
- Denial – Shock and disbelief
- Anger – struggling with fate(Why me? Or It’s not fair!)
- Bargaining – making deals with a higher power in the hope of a cure
- Depression and despair – realizing that death is inevitable
- Acceptance – succumbing to fate with relative calmness
Stages of Grief
- Avoidance (numbing and blunting)
- Confrontation (disorganization and despair)
- Reestablishment (reorganization and recovery)
Chronic Sorrow
- a form of grief that often includes characteristics of other forms of grief but that differs with regard to several essential aspects.
- 1st chronic sorrow is a response to ongoing loss; 2nd persons who are experiencing chronic sorrow seldom experience disability
- Who would be at risk? Parents with children with mental disabilities, schizophrenia, or other chronic illness; spouses of persons with long term chronic illnesses, such as multiple sclerosis alcoholism, or AD; and persons with similar disorders
Primary (Irreversable) Dementia
Alzeimer’s Disease, Vascular Dementia, Picks Disease, Huntington’s Disease
Parkinson’s Dementia, Creutzfeidt-Jakob disease
Dementia: Reversible (secondary)
Delirium, Depression, Amnestic disorders, Tumors, Infection, Trauma, Some cerebral emboli
Recent memory loss but keeps long term memory
Stage 1: Mild (2-4 years)
- Patients have problems naming common items, they repeat things, and they lose things easily, and they get lost frequently.
Stage 1: Mild (2-4 years)
Inability to find words and the use of inappropriate words
Stage 1: Mild (2-4 years)
Neologism – invented and meaningless words
Stage 1: Mild (2-4 years)
Show signs of personality changes
Stage 1: Mild (2-4 years)
They are self awareness of loss that many patients suffer profound depression
Stage 1: Mild (2-4 years)
Intellectual decline continues to increase and includes amnesia, disorientation, apriaxia, aphasia, and depression
Stage 2: Moderate (2-10 years)
Lead to the loss of the ability to care for oneself
Stage 2: Moderate (2-10 years)
Difficulty making decision as a result of decreased concentration
Stage 2: Moderate (2-10 years)
Lack the cognitive skills to make appropriate judgments
Stage 2: Moderate (2-10 years)
Develop delusion that are paranoid in nature
Stage 2: Moderate (2-10 years)
Both short- and long-term memory are affected
Stage 2: Moderate (2-10 years)