Test 4 Flashcards

1
Q

Tc cell differs from Th cell in that

A

Tc cell once activated will search for infected cells to destroy while Th cells activate other immune cells in response.

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2
Q

Selective toxicity

A

target pathogens leave host cells unharmed

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3
Q

which most likely accounts for antibiotic resistance?

A

indiscriminate use of antibiotics

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4
Q

mechanisms of action of antibiotics?

A

interfere with cell wall synthesis
interfere will protein synthesis
interfere with nucleic acid synthesis

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5
Q

antibiotic in animal feed leads to antibiotic resistance in bacteria because

A

antibiotic kills susceptible bacteria but few that are naturally resistant live and reproduce and their progeny repopulate the host cell

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6
Q

best describe definition of virulence for pathogen

A

ability to invade, spread, establish an infection, damage it causes doing so

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7
Q

sequence reaction initiated after a phagocytic cell engulfs invading microbes

A

complement cascade

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8
Q

which of these immune responses may directly contribute to bacterial endotoxin release by cell lysis?

A

MAC formation

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9
Q

During what viral processes does a point mutation occur that contribute to the antigenic DRIFT?

A

translation by host ribosome

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10
Q

benefit of normal microbiota

A

competition for nutrition against pathogen

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11
Q

recognized or classified as a PAMP recognized by PRR

A

G+ teichoic acid
G- LPS
RNA double stranded viral genome

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12
Q

adaptive immune system activity

A

occurs in lymph nodes

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13
Q

how does MAC affect G- cells?

A

G- cells have outer membrane that is targeted by MAC

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14
Q

classified as opsonin

A

antibody

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15
Q

a single antibody can bind to any antigen

A

false

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16
Q

get bitten by a bug and gets yellow fever and has not been vaccinated. What type of immune defense against pathogen during first week of infection?

A

innate because it will react to the first time infected

17
Q

IgA transferred thru breast milk absorbed into the blood but present in the mucus membrane to protect the infant. since phagocytes and complement proteins do not reside in mucus. What is the main function of IgA antibody?

A

prevention of attachment

18
Q

MCH I was prevented from being displayed on the cell surface. What would be the result?

A

Tc cell would not monitor the cell for infection

NK would identify the lack of MHC I and kill the cell

19
Q

What is not true of memory cells?

A

memory cells are NK cells

20
Q

ability of population to resist severe epidemic b.c of significant proportion of its

A

herd immunity

21
Q

which one of this is not a professional APC?

A

NR cell (does she mean NK cell?)

22
Q

Humoral immunity is carried out by __ while cell-mediated immunity is mainly carried out by ___

A

B cell; T cell

23
Q

Not an example of host’s innate protection against microbial invasion

A

antibodies

24
Q

Mutation occurs that knocks out formation of complement protein C3b. Which of the following activities would be less effective?

A

complement activation

opsonization