Test 4 Flashcards
Tc cell differs from Th cell in that
Tc cell once activated will search for infected cells to destroy while Th cells activate other immune cells in response.
Selective toxicity
target pathogens leave host cells unharmed
which most likely accounts for antibiotic resistance?
indiscriminate use of antibiotics
mechanisms of action of antibiotics?
interfere with cell wall synthesis
interfere will protein synthesis
interfere with nucleic acid synthesis
antibiotic in animal feed leads to antibiotic resistance in bacteria because
antibiotic kills susceptible bacteria but few that are naturally resistant live and reproduce and their progeny repopulate the host cell
best describe definition of virulence for pathogen
ability to invade, spread, establish an infection, damage it causes doing so
sequence reaction initiated after a phagocytic cell engulfs invading microbes
complement cascade
which of these immune responses may directly contribute to bacterial endotoxin release by cell lysis?
MAC formation
During what viral processes does a point mutation occur that contribute to the antigenic DRIFT?
translation by host ribosome
benefit of normal microbiota
competition for nutrition against pathogen
recognized or classified as a PAMP recognized by PRR
G+ teichoic acid
G- LPS
RNA double stranded viral genome
adaptive immune system activity
occurs in lymph nodes
how does MAC affect G- cells?
G- cells have outer membrane that is targeted by MAC
classified as opsonin
antibody
a single antibody can bind to any antigen
false
get bitten by a bug and gets yellow fever and has not been vaccinated. What type of immune defense against pathogen during first week of infection?
innate because it will react to the first time infected
IgA transferred thru breast milk absorbed into the blood but present in the mucus membrane to protect the infant. since phagocytes and complement proteins do not reside in mucus. What is the main function of IgA antibody?
prevention of attachment
MCH I was prevented from being displayed on the cell surface. What would be the result?
Tc cell would not monitor the cell for infection
NK would identify the lack of MHC I and kill the cell
What is not true of memory cells?
memory cells are NK cells
ability of population to resist severe epidemic b.c of significant proportion of its
herd immunity
which one of this is not a professional APC?
NR cell (does she mean NK cell?)
Humoral immunity is carried out by __ while cell-mediated immunity is mainly carried out by ___
B cell; T cell
Not an example of host’s innate protection against microbial invasion
antibodies
Mutation occurs that knocks out formation of complement protein C3b. Which of the following activities would be less effective?
complement activation
opsonization
