test 3 part 5 Flashcards
sx of lambert eaton syndrome
- proximal muscle weakness in pelvic and truncal areas
- bulbar dysfx
- decreased DTR
- posttetanic potential of muscle contraction
- muscle weakness is more significant in the morning and usually improves throughout the day
Eaton-Lambert syndrome is most often associated with carcinomas, particularly ___________________
small cell lung cancer
with myasthenia gravis sx are improved with ________________ or ___________; with eaton-lambert syndrome, sx are improved with _______________
anticholinesterases; steroids; activity
tx of Eaton-Lambert syndrome?
- therapeutic goal is to increase amount of ACh in the synaptic cleft
- potassium channel blockers
- acetylcholinesterase inhib
- immunologic therapies
- Tx underlying malignancy
________________ is a group of x-linked recessive mutation in the dystrophin gene
muscular dystrophy
_______________, pts will present with progressive proximal muscle weakness and wasting. most are wheelchair bound by age 12
muscular dystrophy
what do most patients with muscular dystrophy die from? and by what age?
2ndary cardiopulmonary failure by age 30
treatment for muscular dystrophy
no cure, supportive tx
perioperative complications to expect with muscular dystrophy
rhabdomyolysis
hyperkalemia
malignant hyperthermia
cardiac arrest
__________________ is characterized by an elevation in serum creatinine and myopathic pattern on EMG
muscular dystrophy
muscular dystrophy anesthetic complications
- CV evaluation for progressive cardiomyopathy and fx’al status
- pulmonary eval for restrictive lung disease/compromise
- risk for aspiration
- avoid succ
- avoid malignant hyperthermia triggering agents (succ, halogenated inhalation agents)
what should be your anesthetic plan for pt with muscular dystrophy
TIVA
anesthesia considerations for myotonia
- cold environment may trigger
- high incident of PPC
- avoid DMR
- NMDR okay
- Avoid etomidate
- risk for malignant hyperthermia
T/F: over 80% of perioperative strokes occur in the postoperative period
true
where doe most nose bleeds occur
anterior portion of the nose of the ICA and ECA (kiesselbachs plexus)
which type of nose bleed can you typically stop by holding pressure on the cartilaginous part of the nose or with some neosynephrine
anterior
which type of nose bleed is hard to treat, may require embolization, surgery, silver nitrate, ballooning and/or packing
posterior
which nose bleed has greater risk of airway compromise d/t blood in both nostrils and the posterior pharynx
posterior
posterior nose bleed is usually due to damage to which artery
sphenopalantine
larynx of an adult is located at C__________
4-6
enlargement of this tonsil is usally a compensatory mechanism after tonsillectomy or with autoimmune d/o and if enlarged will cause UNANTICIPATED difficult airway
lingual tonsils
at what cervical vertebrae is the larynx located in an infant
C3-C4 (more anterior)
what is the only complete ring in the upper airway
cricoid cartilage
the cricoarytenoid joint is a _____________ joint; thus can be an issue with what disease process
synovial; RA