Test 3 Flashcards
Liver, Gall Bladder, Pancreas, Renal, Neuro, Renal Peds, Neuro Peds
Functions of the liver (8)
- Glucose metabolism (gluconeogenesis)
- Ammonia conversion (excreted in urine)
- Protein metabolism
- Fat metabolism
- Vitamin and Iron storage
- Bile formation (bile salts from cholesterol help increase fat digestion)
- Bilirubin excretion (increased levels in blood indicate liver disease)
- Drug metabolism**
Organ that is important in the regulation of glucose and protein metabolism, and secretes bile
The liver
Caused by exposure to hepatotoxic chemicals, meds, and botanical agents
Toxic Hepatitis
Signs and Symptoms of Toxic Hepatitis
Anorexia
Nausea/vomiting
Jaundice
Hepatomegaly
This hepatitis has no effective antidote and has rapid recovery if toxin is removed early
Toxic Hepatitis
Most common cause of acute liver failure
Drug-induced Hepatitis
True hepatotoxins (4)
- Carbon tetrachloride
- Phosphorus
- Chloroform
- Gold compounds
Drug-induced hepatitis clinical manifestations
Chills, fever Rash, pruritis Arthralgia Anorexia, vomiting Jaundice, dark urine, enlarged liver (late stages)
Sudden and severely impaired liver function in a previously healthy person
Fulminant Hepatic Failure
Most common cause of fulminant hepatic failure
Viral hepatitis
Can also be cause by: toxic meds, chemical exposure, metabolic disturbances
Replacement of normal liver tissue with diffuse fibrosis
Cirrhosis
Clinical manifestations of hepatitis
Fever Fatigue Anorexia/loss of appetite Nausea, vomiting Abdominal pain Gray-colored stools Joint pain Jaundice
Types of cirrhosis (3)
- Alcoholic - most common (scar tissue around portal areas)
- Post-necrotic - acute viral hepatitis (broad bands of scar tissue)
- Biliary - chronic biliary obstruction and infection (scar tissue around biliary ducts)
Cirrhosis nursing care
Promote rest Improve nutrition Provide skin care Decrease injury risk Monitor for complications (bleeding, hepatic encephalopathy, fluid excess)
Hepatic cirrhosis is diagnosed by…
Liver biopsy
Symptoms of hepatic dysfunction
Jaundice Ascites Esophageal varices Hepatic encephalopathy and coma Edema and bleeding Vitamin deficiency Metabolic disorders Pruritis/skin changes Liver abscess
Caused by an elevated bilirubin blood level
Jaundice (greater than 2.5)
Movement of fluid into the peritoneal cavity
Ascites
Contributing factors to Ascites (3)
Portal hypertension
Increased capillary pressure
Obstruction of venous blood through liver
Commonly manifested by increased abdominal girth and weight gain
Ascites
Assessment of ascites
Percussion differences, daily weight and abdominal girth measurements
Management of ascites
Decreased fluid intake Diuretics (aldactone) Decreased sodium diet Paracentesis Bed rest Electrolyte monitoring
Development of dilated tortuous veins in the esophagus
Esophageal varices
Manifested by coughing, throat discomfort, and spitting up blood
Bleeding esophageal varices (can result in hemorrhagic shock)