Test 2 - Enzymes (Corrected) Flashcards
1
Q
Catalysis by proximity
A
- Substrate molecules are in the active site of enzymes
- Support:
- If you can bring enzymes closer to their substrates, then the reaction will move faster.
- In example C the esthers are already close to each other so they can be catalyzed faster.
- Role in Substrate Channeling
- Substrates are channeled that way the concentration of substrates and intermediates is kept high as it moves from one enzyme to the next.
2
Q
Acid - Base Catalysis
A
- Side chains and prosthetic groups contribute to catalysis by acting as acids and bases.
- Presence of Asp, Glu, Lys, Arg, His.
3
Q
Coenzyme A
A
- Transfers: Acyl groups
- Precursor: Pantothenic acid and other compounds.
4
Q
FAD
A
- Flavin Adenine dinucleotide
- Transfer: Electrons
- Precursor: Riboflavin (Vit. B2)
5
Q
Lipoate
A
- Transfers: Electrons and Acyl groups
- Precursor: No dietary
6
Q
NAD
A
- Nicotinamide adenine dinucleotide
- Transfer: Hydride Ion ( :H -)
- Precursor: Nicotinic Acid (Niacin)
- Mobile Universal electron carrier
7
Q
Thiamine pyrophosphate
A
- Transfer: Aldehydes
- Precursor: Thiamine (Vit. B1)
8
Q
Tetrahydrofolate
A
- Transfer: One carbon groups.
9
Q
What type of inhibition does this graph show?
A
Competitive
10
Q
What type of inhibition is this equation?
A
Competitive
11
Q
What type of inhibition is this graph
A
Mixed inhibition graph
12
Q
What type of inhibition is the following graph?
A
Uncompetitive
13
Q
What does competitive inhibition effect?
A
Negatively impacts Km
14
Q
What does mixed or noncompetitive inhibition effect?
A
Decreases maximum Velocity.
15
Q
What does uncompetitive inhibition affect?
A
Decreases both Km and Vmax.
